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Recombinant Mesocricetus auratus Free fatty acid receptor 1 (FFAR1)

  • 中文名稱：
    Recombinant Mesocricetus auratus Free fatty acid receptor 1(FFAR1)
  • 貨號：
    CSB-CF008604MRG
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
  • Uniprot No.：
  • 別名：
    FFAR1; GPR40; Free fatty acid receptor 1; G-protein coupled receptor 40
  • 種屬：
    Mesocricetus auratus (Golden hamster)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-300
  • 氨基酸序列
    MALSPQLFFALYVSAFALGFPLNLLAIRGAVARARLRLTPNLVYTLHLACSDLLLAITLP VKAVEALASGAWPLPLPLCPVFVLVHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAVRRP RYSWGVCVAIWALVLCHMGLVLGLEAPGGWLNTTSSSLGINTPVNGSPVCLEAWDPNSAR PARLSFSILLFFVPLVITAFCYVGCLRALAHSGLSHKRKLRAAWAAGGAFLTLLLCLGPY NASNVASFVNPDLGGSWRKLGLITGSWSVVLNPLVTGYLGASPGRGTVCTTRTQGGTIQK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. Mediates the anti-inflammatory effects of omega-3 polyunsaturated fatty acids (PUFAs) via inhibition of NLRP3 inflammasome activation.
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family