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  4. Recombinant Mouse G-protein coupled receptor family C group 5 member C (Gprc5c)

Recombinant Mouse G-protein coupled receptor family C group 5 member C (Gprc5c)

  • 中文名稱：
    小鼠Gprc5c重組蛋白
  • 貨號：
    CSB-CF818347MO
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產品詳情

  • 基因名：
  • Uniprot No.：
  • 別名：
    Gprc5c; Raig3; G-protein coupled receptor family C group 5 member C; Retinoic acid-induced gene 3 protein; RAIG-3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    23-440
  • 氨基酸序列
    QNHAPPGCSPDLDPLYYNLCDRSGAWGIVSEAVAGAGIITTFVLTIILVASLPFVQDTKK RSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLVAHVLSLNF LTRKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGGGQVSPLGNVSADSTMTSPCA IANMDFVMALIYVMLLLLTAFLGAWPTLCGRFKRWRKHGVFVLLTTVISIAIWVVWIVMY TYGNEQHHSPTWDDPTLAIALAANAWTFVLFYVIPEVSQVTKPSPEQSYQGDMYPTRGVG YETILKEQTGQSMFVENKAFSMDEPASAKRPVSPYSGYNGQLLTSVYQPTEMALMHKGPS EGAYDVILPRATANSQVMGSANSTLRAEDMYMVQSHQVATPPKDGKISQVFRNPYVWD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 10xHis-tagged
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • 基因功能參考文獻：
    1. Gprc5c KO mice have altered acid-base homeostasis and reduced NHE3 activity in the kidney. PMID: 29196502
    2. Data suggest that agents (such as all-trans retinoic acid) that activate Gprc5c restore and/or maintain functional insulin-secreting cells; Gprc5c appears to play role in regulation of expression of genes controlling apoptosis, cell survival, and cell proliferation in insulin-secreting cells. PMID: 28228611
    3. GPRC5C does not affect behavior, though it has a high sequence similarity to GPRC5B. PMID: 21840300
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 3 family
  • 數(shù)據(jù)庫鏈接：