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  4. Recombinant Mouse Integral membrane protein 2A (Itm2a)-VLPs

Recombinant Mouse Integral membrane protein 2A (Itm2a)-VLPs

  • 中文名稱：
    小鼠Itm2a重組蛋白
  • 貨號：
    CSB-MP011903MO
  • 規(guī)格：
  • 其他：

產(chǎn)品詳情

  • 基因名：
    Itm2a
  • Uniprot No.：
  • 別名：
    Itm2a; E25; Itm2; Integral membrane protein 2A; Protein E25
  • 種屬：
    Mus musculus (Mouse)
  • 來源：
    Mammalian cell
  • 表達(dá)區(qū)域：
    1-263aa
  • 氨基酸序列
    MVKIAFNTPTAVQKEEARQDVEALVSRTVRAQILTGKELRVVPQEKDGSSGRCMLTLLGLSFILAGLIVGGACIYKYFMPKSTIYHGEMCFFDSEDPVNSIPGGEPYFLPVTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLDLLLGNCYLMPLNTSIVMTPKNLVELFGKLASGKYLPHTYVVREDLVAVEEIRDVSNLGIFIYQLCNNRKSFRLRRRDLLLGFNKRAIDKCWKIRHFPNEFIVETKICQE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    C-terminal 10xHis-tagged
    If you have specified tag type, please tell us and we will check if it’s possible to develop.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will default ship it in lyophilized form with normal bule ice packs. However, if you request to ship in liquid form, it needs to be shipped with dry ice, please communicate with us in advance and extra fees for dry ice and dry ice box will be charged.
  • 緩沖液：
    Lyophilized from PBS, 6% Trehalose, pH 7.4
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store the protein at -20°C/-80°C upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. Itm2a knockdown is sufficient to rescue the inhibitory effects of lamin A WT and R482W mutant overexpression on 3T3-L1 differentiation. PMID: 28872940
    2. Itm2a possesses diverse functional properties as evidenced by differential expression during odontogenesis. PMID: 25079563
    3. Itm2a is a target gene of GATA-3 that plays a minimal role in regulating the development and function of T cells PMID: 24831988
    4. Itm2a is not only expressed in adult muscle fibres but also in the satellite cells responsible for regeneration. PMID: 23650549
    5. Results support the involvement of Itm2a in the early stages of chondrogenesis in vitro. PMID: 15325075
    6. Both Itm2a and Itm2c were not detected in the epididymis and vas deferens during sexual maturation. PMID: 17873332

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  • 亞細(xì)胞定位：
    Membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    ITM2 family
  • 組織特異性：
    Expressed in mandibular condyles, in bone and in hair follicles. Strong expression in osteogenic tissues, such as neonatal calvaria, paws, tail and skin.
  • 數(shù)據(jù)庫鏈接：

    KEGG: mmu:16431

    STRING: 10090.ENSMUSP00000033591

    UniGene: Mm.193