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  4. Recombinant Pig Kynurenine 3-monooxygenase (KMO)

Recombinant Pig Kynurenine 3-monooxygenase (KMO)

  • 中文名稱：
    野豬KMO重組蛋白
  • 貨號(hào)：
    CSB-CF873551PI
  • 規(guī)格：
  • 來(lái)源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    KMO
  • Uniprot No.：
  • 別名：
    KMO; Kynurenine 3-monooxygenase; Fpk; Kynurenine 3-hydroxylase
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-471
  • 氨基酸序列
    MDSSDIQRTSIAVIGGGLVGSLNACFLAKRNFQVDVYESREDIRMAEFARGRSINLALSY RGRQALKAIGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSISRENLNKDLLT AVEKYPNAKVHFGHQLLKCRPETGVITLLGPDKVPKDIACDLILGCDGAYSTVRTHLVKK PRFDYSQQYIPHGYMELTIPPQNGDFAMEPNYLHIWPRDTFMMIALPNMNKSFTCTLFMP FEEFEKLLTSRDVLDFFQKYFPDSLHLIGKEALAQDFFRLPAQPMISVKCSSFHFNSHCV LMGDAAHALVPFFGQGMNAGFEDCLVFDELMDKFNNDFSMCLPEFSKFRIPDDHAISDLS MYNYIEMRSHVNSRWFIFQKNIERCLHTLMPSTFIPLYTMVTFSRIRYHEAMLRWQWQKK VINTALFFFGTLVALSTTYLLTGPTFRSSLGCLRRSWNSVTYFQNIGRISL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
  • 基因功能參考文獻(xiàn)：
    1. The carboxyl-terminal region of pig liver L-kynurenine 3-monooxygenase plays a dual role as a mitochondrial-targeting signal and an enzyme. PMID: 20802227
  • 亞細(xì)胞定位：
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Aromatic-ring hydroxylase family, KMO subfamily
  • 數(shù)據(jù)庫(kù)鏈接：