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ABCG2

ABCG2,即ATP結(jié)合盒亞家族G成員2,別名CD338、CDw338、MXR、MXR1。它是一種由ABCG2基因編碼的跨膜轉(zhuǎn)運(yùn)蛋白,屬于ATP結(jié)合盒(ABC)轉(zhuǎn)運(yùn)蛋白家族。ABCG2在多種組織中表達(dá),包括腸道、胎盤、肝臟和腫瘤細(xì)胞。其作用機(jī)制是通過ATP水解提供能量,將多種底物,包括藥物、代謝產(chǎn)物等從細(xì)胞內(nèi)運(yùn)輸?shù)郊?xì)胞外,影響藥物的吸收、分布和排泄。ABCG2參與調(diào)節(jié)細(xì)胞內(nèi)外物質(zhì)的平衡,對(duì)藥物耐藥性、細(xì)胞解毒、免疫調(diào)節(jié)和炎癥反應(yīng)等過程具有重要作用。ABCG2的異常表達(dá)或功能失調(diào)與多種疾病相關(guān),包括腫瘤的多藥耐藥性、高尿酸血癥和痛風(fēng)等。

熱銷產(chǎn)品

Recombinant Human Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2), partial (CSB-YP891568HU1)

驗(yàn)證數(shù)據(jù)

CSB-YP891568HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ABCG2 Antibody (CSB-PA891568LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA891568LA01HU

Immunofluorescent analysis of A549 cells using CSB-PA891568LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human ATP-binding cassette transporter G2,ABCG2 ELISA Kit (CSB-E11251h)

驗(yàn)證數(shù)據(jù)

CSB-E11251h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E11251h

規(guī)格:96T/48T

靈敏度:0.039 ng/mL

檢測(cè)范圍:0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ABCG2 Antibodies

ABCG2 for Homo sapiens (Human)

ABCG2 Proteins

ABCG2 Proteins for Bos taurus (Bovine)

ABCG2 Proteins for Macaca mulatta (Rhesus macaque)

ABCG2 Proteins for Mus musculus (Mouse)

ABCG2 Proteins for Rattus norvegicus (Rat)

ABCG2 Proteins for Sus scrofa (Pig)

ABCG2 Proteins for Dictyostelium discoideum (Slime mold)

ABCG2 Proteins for Homo sapiens (Human)

ABCG2 ELISA Kit

ABCG2 ELISA Kit for Homo sapiens (Human)