ACKR3
ACKR3，全稱為非典型趨化因子受體3，也被稱為Rdc1、Cxcr7等。該蛋白主要參與細(xì)胞增殖、炎癥反應(yīng)等生物學(xué)過程。ACKR3在腫瘤惡液質(zhì)中發(fā)揮關(guān)鍵作用，與腫瘤細(xì)胞分泌的MIF相互作用，激活脂肪干細(xì)胞的炎癥反應(yīng)，導(dǎo)致脂肪組織不可逆損失。此外，ACKR3還與癌癥、心血管疾病等疾病相關(guān)。目前，針對ACKR3的藥物研發(fā)正在積極推進(jìn)，有望為相關(guān)疾病的治療提供新的策略。
熱銷產(chǎn)品
Recombinant Human Atypical chemokine receptor 3 (ACKR3), partial (CSB-EP006257HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數(shù)據(jù)
Western Blot analysis of COS7 cells using CXCR-7 Polyclonal Antibody
ACKR3 Antibodies
ACKR3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006257GA01HU | ACKR3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA001850 | ACKR3 Antibody | Human,Mouse,Rat,Monkey | WB, IF, ELISA |
ACKR3 Proteins
ACKR3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006257DO1 CSB-EP006257DO1 CSB-BP006257DO1 CSB-MP006257DO1 CSB-EP006257DO1-B |
Recombinant Dog C-X-C chemokine receptor type 7 (CXCR7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF006257DO | Recombinant Dog C-X-C chemokine receptor type 7 (CXCR7) | in vitro E.coli expression system |
ACKR3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006257HU CSB-BP006257HU CSB-MP006257HU CSB-EP006257HU-B |
Recombinant Human Atypical chemokine receptor 3 (ACKR3), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006257HU | Recombinant Human Atypical chemokine receptor 3 (ACKR3), partial | E.coli |
| CSB-CF006257HU(A4) | Recombinant Human Atypical chemokine receptor 3 (ACKR3) | in vitro E.coli expression system |
| CSB-MP006257HU(A4) | Recombinant Human Atypical chemokine receptor 3 (ACKR3)-VLPs | Mammalian cell |
ACKR3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006257MO1 CSB-EP006257MO1 CSB-BP006257MO1 CSB-MP006257MO1 CSB-EP006257MO1-B |
Recombinant Mouse C-X-C chemokine receptor type 7 (Cxcr7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF006257MO | Recombinant Mouse C-X-C chemokine receptor type 7 (Cxcr7) | in vitro E.coli expression system |
ACKR3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006257RA1 CSB-EP006257RA1 CSB-BP006257RA1 CSB-MP006257RA1 CSB-EP006257RA1-B |
Recombinant Rat C-X-C chemokine receptor type 7 (Cxcr7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF006257RA | Recombinant Rat C-X-C chemokine receptor type 7 (Cxcr7) | in vitro E.coli expression system |
