ADGRL2
ADGRL2，全稱為adhesion G protein-coupled receptor L2，也被稱為LPHN2或latrophilin 2。這是一種黏附類G蛋白偶聯受體，主要參與細胞結構的構成和多項細胞生命活動，如細胞黏附、遷移、物質運輸、細胞分化和凋亡等。ADGRL2在多種細胞類型中表達，包括內皮細胞、神經元和免疫細胞。其與α-latrotoxin等配體結合，通過G蛋白信號通路介導細胞內信號轉導。ADGRL2的表達與心血管疾病、神經系統發(fā)育和疾病以及腫瘤發(fā)生和發(fā)展相關，因此成為藥物研發(fā)的重要靶點。目前，針對ADGRL2的藥物研發(fā)主要集中在調節(jié)其活性，以治療相關疾病。
熱銷產品
ADGRL2 Antibody (CSB-PA013060ESR2HU)
驗證數據
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA013060ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA013060ESR2HU at dilution of 1:100
ADGRL2 Antibodies
ADGRL2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA008347 | LPHN2 Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA013060ESR2HU | ADGRL2 Antibody | Human | ELISA, IHC |
ADGRL2 Proteins
ADGRL2 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013060BO CSB-EP013060BO CSB-BP013060BO CSB-MP013060BO CSB-EP013060BO-B |
Recombinant Bovine Latrophilin-2 (LPHN2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRL2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013060RA CSB-EP013060RA CSB-BP013060RA CSB-MP013060RA CSB-EP013060RA-B |
Recombinant Rat Latrophilin-2 (Lphn2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRL2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013060HU CSB-EP013060HU CSB-BP013060HU CSB-MP013060HU CSB-EP013060HU-B |
Recombinant Human Latrophilin-2 (LPHN2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRL2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP811675MO CSB-EP811675MO CSB-BP811675MO CSB-MP811675MO CSB-EP811675MO-B |
Recombinant Mouse Latrophilin-2 (Lphn2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
