ALDH3A2
ALDH3A2，即醛脫氫酶3家族成員A2，別名FALDH、ALDH10、SLS等。這個(gè)基因位于人類17號(hào)染色體上，編碼的蛋白質(zhì)主要負(fù)責(zé)催化長(zhǎng)鏈脂肪醛氧化為脂肪酸。ALDH3A2的作用機(jī)制是通過其酶活性，參與氧化長(zhǎng)鏈脂肪醛，對(duì)維持細(xì)胞內(nèi)脂質(zhì)代謝平衡和清除有毒醛類物質(zhì)具有重要作用。ALDH3A2在多種組織中廣泛表達(dá)，尤其是在皮膚、腎上腺等組織中表達(dá)量較高。ALDH3A2突變可導(dǎo)致舍格倫-拉格倫綜合癥（Sjogren-Larsson Syndrome），這是一種罕見的遺傳性疾病，表現(xiàn)為皮膚、神經(jīng)系統(tǒng)和眼部的異常。此外，ALDH3A2在腫瘤的發(fā)生發(fā)展中也扮演著重要角色，其表達(dá)水平在多種腫瘤中發(fā)生變化，可作為潛在的腫瘤生物標(biāo)志物和治療靶點(diǎn)。
熱銷產(chǎn)品
ALDH3A2 Antibody (CSB-PA090286)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA090286(ALDH3A2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human normal liver and fetal liver tissue, Primary antibody: CSB-PA090286(ALDH3A2 Antibody) at dilution 1/250 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
ALDH3A2 Antibodies
ALDH3A2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001573GA01HU | ALDH3A2 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA090286 | ALDH3A2 Antibody | Human | ELISA,WB,IHC |
| CSB-PA033785 | ALDH3A2 Antibody | Human | ELISA,WB,IHC |
ALDH3A2 Proteins
ALDH3A2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001573HU1 CSB-EP001573HU1 CSB-BP001573HU1 CSB-MP001573HU1 CSB-EP001573HU1-B |
Recombinant Human Aldehyde dehydrogenase family 3 member A2 (ALDH3A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF001573HU | Recombinant Human Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) | in vitro E.coli expression system |
