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BTN3A1

BTN3A1,即嗜乳脂蛋白亞家族3成員A1,別名BTF5、BT3.1、CD277、BTN3.1。BTN3A1由人類BTN3A1基因編碼,該基因位于6號染色體的p22.2區(qū)域。BTN3A1的作用機(jī)制涉及與γδT細(xì)胞的相互作用,參與調(diào)控它們的活化和功能,尤其在免疫調(diào)控的起始階段具有重要作用。BTN3A1在細(xì)胞黏附、抗原呈遞和免疫細(xì)胞激活等方面展現(xiàn)了革命性的潛力,特別是在調(diào)節(jié)γδT細(xì)胞激活方面,它與γδT細(xì)胞相互作用,影響免疫細(xì)胞的識別和應(yīng)答,從而影響免疫系統(tǒng)的記憶和持久性反應(yīng)。BTN3A1為腫瘤免疫治療提供了新的靶點。

熱銷產(chǎn)品

Recombinant Human Butyrophilin subfamily 3 member A1 (BTN3A1), partial (CSB-EP002873HUb0)

驗證數(shù)據(jù)

CSB-EP002873HUb0

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

BTN3A1 Antibody (CSB-PA002873LA01HU)

驗證數(shù)據(jù)

CSB-PA002873LA01HU

Western Blot
Positive WB detected in: U937 whole cell lysate, K562 whole cell lysate, 293 whole cell lysate, A549 whole cell lysate
All lanes: BTN3A1 antibody at 1: 1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 40-58 kDa
Observed band size: 48 kDa

CSB-PA002873LA01HU

Immunofluorescence staining of Hela cell with CSB-PA002873LA01HU at 1:20, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA002873LA01HU

Immunofluorescence staining of Hela cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA002873LA01HU

Immunofluorescence staining of SH-SY5Y cell with CSB-PA002873LA01HU at 1:20, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA002873LA01HU

Immunofluorescence staining of SH-SY5Y cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

BTN3A1 Antibodies

BTN3A1 for Homo sapiens (Human)

BTN3A1 Proteins

BTN3A1 Proteins for Homo sapiens (Human)