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CCL19

CCL19,即C-C基序趨化因子配體19,別名ELC、CKb11、MIP3B、MIP-3b、SCYA19。CCL19是一種分泌型蛋白,屬于CC亞家族的趨化因子,通過與趨化因子受體CCR7特異性結(jié)合發(fā)揮作用。CCL19在胸腺和淋巴結(jié)中高表達(dá),在氣管和結(jié)腸中中等表達(dá),在胃、小腸、肺、腎和脾中低表達(dá)。CCL19在正常淋巴細(xì)胞再循環(huán)和歸巢中發(fā)揮作用,對(duì)T細(xì)胞在胸腺中的運(yùn)輸以及T細(xì)胞和B細(xì)胞向次級(jí)淋巴器官的遷移具有重要作用。CCL19還參與免疫調(diào)節(jié)和炎癥過程,影響免疫細(xì)胞釋放抗病毒相關(guān)細(xì)胞因子,促進(jìn)T細(xì)胞增殖和樹突狀細(xì)胞對(duì)抗原的攝取。

熱銷產(chǎn)品

Recombinant Human C-C motif chemokine 19 (CCL19) (CSB-EP859522HU)

驗(yàn)證數(shù)據(jù)

CSB-EP859522HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CCL19 Recombinant Monoclonal Antibody (CSB-RA859522A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA859522A0HU

IHC image of CSB-RA859522A0HU diluted at 1:155 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-RA859522A0HU

IHC image of CSB-RA859522A0HU diluted at 1:155 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CCL19 Antibodies

CCL19 for Homo sapiens (Human)

CCL19 Proteins

CCL19 Proteins for Mus musculus (Mouse)

CCL19 Proteins for Homo sapiens (Human)

CCL19 ELISA Kit

CCL19 ELISA Kit for Mus musculus (Mouse)

CCL19 ELISA Kit for Homo sapiens (Human)