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CCN2

CCN2,即結(jié)締組織生長因子,別名CTGF。它是一種在多種細(xì)胞類型中表達(dá)的蛋白質(zhì),尤其在心臟、肺、肝、腎和實體器官移植中發(fā)揮作用。CCN2在細(xì)胞增殖、分化、粘附和血管生成等生物過程中起調(diào)控作用,同時參與腫瘤發(fā)展、組織纖維化等多種病理過程。CCN2的作用機(jī)制涉及與細(xì)胞表面的整合素受體結(jié)合,激活如FAK信號通路,進(jìn)而影響細(xì)胞行為和代謝。CCN2在胚胎發(fā)育、組織再生、纖維化反應(yīng)以及腫瘤微環(huán)境中扮演重要角色。其異常表達(dá)與多種疾病的發(fā)生發(fā)展相關(guān),包括纖維化疾病、心血管疾病和癌癥等,因此CCN2也是藥物開發(fā)的重要靶點之一。

熱銷產(chǎn)品

Recombinant Human CCN family member 2 (CCN2), partial (CSB-EP006147HU1)

驗證數(shù)據(jù)

CSB-EP006147HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CTGF Antibody (CSB-PA09429A0Rb)

驗證數(shù)據(jù)

CSB-PA09429A0Rb

Immunofluorescent analysis of HepG2 cells using CSB-PA09429A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

CSB-PA09429A0Rb

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA09429A0Rb at dilution of 1:100

Human connective tissue growth factor (CTGF) ELISA kit (CSB-E07875h)

驗證數(shù)據(jù)

CSB-E07875h 標(biāo)準(zhǔn)曲線

貨號:CSB-E07875h

規(guī)格:96T/48T

靈敏度:1.875 pg/mL

檢測范圍:3.75 pg/mL-120 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CCN2 Antibodies

CCN2 for Homo sapiens (Human)

CCN2 Proteins

CCN2 Proteins for Homo sapiens (Human)

CCN2 ELISA Kit

CCN2 ELISA Kit for Homo sapiens (Human)