CD20

CD20，即B淋巴細(xì)胞抗原，別名MS4A1，是一種在B細(xì)胞表面表達(dá)的跨膜磷蛋白。它在B細(xì)胞的發(fā)育過程中，從前體B細(xì)胞到成熟B細(xì)胞的各個階段均有表達(dá)，但在漿細(xì)胞和造血干細(xì)胞中不表達(dá)。CD20在超過95%的B細(xì)胞淋巴瘤中高度表達(dá)，而在正常組織中表達(dá)較低，使其成為治療B細(xì)胞相關(guān)疾病的有效靶點。CD20的作用機制涉及調(diào)節(jié)B細(xì)胞的活化、增殖和分化?？笴D20單克隆抗體，如利妥昔單抗，通過激活補體系統(tǒng)和抗體依賴性細(xì)胞介導(dǎo)的細(xì)胞毒性作用（ADCC）來消滅B細(xì)胞來源的腫瘤細(xì)胞。此外，CD20還參與B細(xì)胞受體（BCR）的信號傳導(dǎo)，與多種細(xì)胞表面蛋白相互作用，對B細(xì)胞的生物學(xué)功能具有重要意義。

熱銷產(chǎn)品

Recombinant Human B-lymphocyte antigen CD20 (MS4A1) (CSB-CF015007HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MS4A1 Recombinant Monoclonal Antibody (CSB-RA015007MA3HU)

驗證數(shù)據(jù)

The Binding Activity of Human MS4A1 with Anti-MS4A1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human MS4A1 (CSB-MP015007HU) at 5 μg/mL can bind Anti-MS4A1 recombinant antibody, the EC₅₀ is 6.959-19.70 ng/mL.

The Binding Activity of Dog MS4A1 with Anti-MS4A1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Dog MS4A1 (CSB-MP661636DO) at 10 μg/mL can bind Anti-MS4A1 recombinant antibody, the EC₅₀ is 147.3-199.0 ng/mL.

The Binding Activity of Macaca fascicularis CD20 with Anti-CD20 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis CD20 (CSB-MP4516MOV) at 10 μg/mL can bind Anti-CD20 recombinant antibody, the EC₅₀ is 10.65-15.26 ng/mL.
The VLPs (CSB-MP3838) is negative control.

CD20 Antibody

CD20 Protein

CD20 ELISA Kit

CD20 Antibodies

CD20 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA015007DSR2HU	MS4A1 Antibody	Human	ELISA, IHC
CSB-PA001433	MS4A1 Antibody	Human	WB, ELISA
CSB-PA006161	MS4A1 Antibody	Human	WB, ELISA
CSB-RA015007A0HU	CD20 Recombinant Monoclonal Antibody	Human	ELISA
CSB-MA996413	MS4A1 Monoclonal Antibody	Human	ELISA, IHC
CSB-RA015007A1HU	MS4A1 Recombinant Monoclonal Antibody	Human	ELISA
CSB-RA015007MA3HU	MS4A1 Recombinant Monoclonal Antibody	Human, Dog, Macaca fascicularis	ELISA
CSB-RA015007MA4HU	MS4A1 Recombinant Monoclonal Antibody	Human	ELISA, IHC, IF

CD20 for H, M, R

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-MA000204	MS4A1 Monoclonal Antibody	Human,Mouse,Rat	ELISA,IHC

CD20 Proteins

CD20 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP015007HU1	Recombinant Human B-lymphocyte antigen CD20 (MS4A1), partial	Yeast
CSB-CF015007HU	Recombinant Human B-lymphocyte antigen CD20 (MS4A1)	in vitro E.coli expression system
CSB-EP015007HU1 CSB-BP015007HU1 CSB-MP015007HU1 CSB-EP015007HU1-B	Recombinant Human B-lymphocyte antigen CD20 (MS4A1), partial	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-MP015007HU	Recombinant Human B-lymphocyte antigen CD20 (MS4A1)-VLPs (Active)	Mammalian cell
CSB-EP015007HU2	Recombinant Human B-lymphocyte antigen CD20 (MS4A1), partial	E.coli
CSB-MP015007HU-D	Recombinant Human B-lymphocyte antigen CD20(MS4A1)-Detergent (Active)	Mammalian cell