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CD74

CD74由長N-末端胞漿側(cè)鏈與短C-末端胞外側(cè)鏈構(gòu)成,含NT、CLIP和CY結(jié)構(gòu)域,胞內(nèi)具酪氨酸/蘇氨酸信號。它運輸MHC II類分子,對免疫識別病原體至關(guān)重要。CD74見于B細胞及某些T細胞,參與淋巴發(fā)育。它激活ERK、PI3K和NF-κB等信號通路,具多種同種型,展現(xiàn)復(fù)雜調(diào)控功能。D74存在多種同種型,可能在不同細胞類型和生理病理條件下發(fā)揮特異性作用。

熱銷產(chǎn)品

Recombinant Human HLA class II histocompatibility antigen gamma chain (CD74), partial (Active)

驗證數(shù)據(jù)

SDS
CSB-MP004956HU1(F2) SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-MP004956HU1(F2) ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD74 at 2 μg/ml can bind Anti-CD74 recombinant antibody (CSB-RA004956A1HU), the EC50 is 1.317-1.646 ng/mL.

Recombinant Mouse H-2 class II histocompatibility antigen gamma chain (Cd74), partial

驗證數(shù)據(jù)

SDS
CSB-BP001262HU1 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LCMS
CSB-BP001262HU1 LCMS-1

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP004956MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Cd74.

LCMS
CSB-BP001262HU1 LCMS-2

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP004956MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Cd74.


CD74 Antibodies

CD74 for Mus musculus (Mouse)

CD74 for Rattus norvegicus (Rat)

CD74 for Homo sapiens (Human)

CD74 Proteins

CD74 Proteins for Rattus norvegicus (Rat)

CD74 Proteins for Homo sapiens (Human)

CD74 Proteins for Mus musculus (Mouse)

CD74 ELISA Kit

CD74 ELISA Kit for Homo sapiens (Human)