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CD8A

CD8A,即分化群8A,別名Leu2、LYT3、MAL等。它來(lái)源于T細(xì)胞在發(fā)育成熟過(guò)程中的表達(dá),是T細(xì)胞表面的一種重要生物標(biāo)志物。CD8A與MHC I類(lèi)分子和TCR相互作用,作為輔助受體,增強(qiáng)T細(xì)胞的抗原識(shí)別與殺傷功能。在腫瘤免疫治療中,CD8A具有重要應(yīng)用價(jià)值,可作為藥物靶點(diǎn),通過(guò)靶向干預(yù)增強(qiáng)腫瘤免疫治療的效果,延長(zhǎng)治療持續(xù)時(shí)間,降低耐藥性,并用于評(píng)估療效。CD8A的生物學(xué)意義在于其作為T(mén)細(xì)胞免疫應(yīng)答的關(guān)鍵分子,對(duì)維持機(jī)體免疫穩(wěn)態(tài)和抗腫瘤免疫至關(guān)重要。

熱銷(xiāo)產(chǎn)品

Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial (CSB-YP004966HU)

驗(yàn)證數(shù)據(jù)

CSB-YP004966HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-YP004966HU

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP004966HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) CD8A.

CSB-YP004966HU

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP004966HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) CD8A.

CD8A Antibody (CSB-PA004966LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA004966LA01HU

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004966LA01HU at dilution of 1:100

CD8A Antibodies

CD8A for Homo sapiens (Human)

CD8A Proteins

CD8A Proteins for Bos taurus (Bovine)

CD8A Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CD8A Proteins for Felis catus (Cat) (Felis silvestris catus)

CD8A Proteins for Mus musculus (Mouse)

CD8A Proteins for Homo sapiens (Human)

CD8A Proteins for Rattus norvegicus (Rat)

CD8A Proteins for Pongo pygmaeus (Bornean orangutan)

CD8A ELISA Kit

CD8A ELISA Kit for Homo sapiens (Human)