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CD9

CD9,即白細(xì)胞分化抗原9,別名MIC3、TSPAN29、GIG2、MRP1等。它是一種多次跨膜的糖蛋白,屬于四跨膜蛋白家族(Tetraspanin),在多種細(xì)胞表面表達(dá),包括白細(xì)胞、血小板、內(nèi)皮細(xì)胞等。CD9的作用機制涉及與多種蛋白質(zhì)相互作用,形成四跨膜蛋白富集的微區(qū)(TEMs),調(diào)控細(xì)胞黏附、細(xì)胞運動、細(xì)胞信號傳導(dǎo)等過程。CD9在細(xì)胞間的相互作用、免疫應(yīng)答、腫瘤轉(zhuǎn)移、精卵融合等過程中發(fā)揮重要作用。例如,在腫瘤細(xì)胞中,CD9的表達(dá)可能與腫瘤的侵襲性和轉(zhuǎn)移能力相關(guān),而在免疫細(xì)胞中,它參與調(diào)節(jié)免疫突觸的形成和細(xì)胞外囊泡的功能。此外,CD9還可能作為某些疾病的治療靶點或生物標(biāo)志物,具有重要的臨床應(yīng)用潛力。

熱銷產(chǎn)品

Recombinant Mouse CD9 antigen (Cd9) (CSB-CF004969MO)

驗證數(shù)據(jù)

CSB-CF004969MO

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CD9 Antibody (CSB-PA004969LA01HU)

驗證數(shù)據(jù)

CSB-PA004969LA01HU

IHC image of CSB-PA004969LA01HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

CD9 Antibodies

CD9 for Homo sapiens (Human)

CD9 Proteins

CD9 Proteins for Bos taurus (Bovine)

CD9 Proteins for Felis catus (Cat) (Felis silvestris catus)

CD9 Proteins for Mus musculus (Mouse)

CD9 Proteins for Rattus norvegicus (Rat)

CD9 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

CD9 Proteins for Sus scrofa (Pig)

CD9 Proteins for Homo sapiens (Human)

CD9 ELISA Kit

CD9 ELISA Kit for Homo sapiens (Human)

CD9 ELISA Kit for Mus musculus (Mouse)