CKAP4
CKAP4，即細(xì)胞骨架相關(guān)蛋白4，別名p63、CLIMP63、ERGIC-63。CKAP4是一種II型跨膜蛋白，主要定位于細(xì)胞膜和粗面內(nèi)質(zhì)網(wǎng)，同時(shí)也是多種配體的受體，在穩(wěn)定蛋白結(jié)構(gòu)中發(fā)揮重要作用。CKAP4參與多種生物活動(dòng)，包括細(xì)胞增殖、細(xì)胞遷移、角質(zhì)形成細(xì)胞分化、糖生成、纖維化、胸腺發(fā)育、心臟發(fā)生、神經(jīng)元凋亡和癌癥的發(fā)生發(fā)展。CKAP4及其亞型與DKK1或DKK3（Dickkopf蛋白）或抗增殖因子（APF）結(jié)合，并調(diào)節(jié)多個(gè)下游信號(hào)通路，如PI3K/AKT和MAPK1/3。CKAP4復(fù)合體在調(diào)節(jié)信號(hào)通路中起關(guān)鍵作用，是癌癥治療的潛在靶點(diǎn)。
熱銷產(chǎn)品
CKAP4 Antibody (CSB-PA005453LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: HepG2 whole cell lysate, Hela whole cell lysate
All lanes: CKAP4 antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 67 kDa
Observed band size: 67 kDa
Immunofluorescence staining of Hela cells with CSB-PA005453LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Human Cytoskeleton-associated protein 4(CKAP4) ELISA kit (CSB-EL005453HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL005453HU
規(guī)格：96T/48T
靈敏度：5.86 pg/mL
檢測(cè)范圍：23.44 pg/mL-1500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CKAP4 Antibodies
CKAP4 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA005453GA01HU | CKAP4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA133590 | CKAP4 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA378255 | CKAP4 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA005453LA01HU | CKAP4 Antibody | Human | ELISA, WB, IF |
| CSB-PA005453LB01HU | CKAP4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA005453LD01HU | CKAP4 Antibody, Biotin conjugated | Human | ELISA |
CKAP4 Proteins
CKAP4 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP005453MO CSB-EP005453MO-B |
Recombinant Mouse Cytoskeleton-associated protein 4 (Ckap4), partial | Yeast In Vivo Biotinylation in E.coli |
| CSB-EP005453MO | Recombinant Mouse Cytoskeleton-associated protein 4 (Ckap4), partial | E.coli |
| CSB-BP005453MO | Recombinant Mouse Cytoskeleton-associated protein 4 (Ckap4), partial | Baculovirus |
| CSB-MP005453MO | Recombinant Mouse Cytoskeleton-associated protein 4 (Ckap4), partial | Mammalian cell |
CKAP4 ELISA Kit
CKAP4 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL005453HU | Human Cytoskeleton-associated protein 4(CKAP4) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 5.86 pg/mL |
