CLDN9
CLDN9，全稱為Claudin-9，是一種緊密連接蛋白，常見別名為DFNB116。它在細(xì)胞間形成緊密連接，維持細(xì)胞極性和信號(hào)傳導(dǎo)。CLDN9在丙型肝炎病毒的進(jìn)入過程中發(fā)揮輔助作用，與聽覺器官中感覺細(xì)胞的保護(hù)有關(guān)，基因缺陷可能與耳聾相關(guān)。此外，CLDN9在腫瘤調(diào)控中扮演重要角色，其高表達(dá)與食管腺癌糖酵解相關(guān)。目前，針對(duì)CLDN9的藥物研發(fā)正在推進(jìn)，有望成為治療癌癥和其他疾病的潛在靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Claudin-9 (CLDN9), partial-Detergent (Active) (CSB-MP005511HU1-D)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CLDN9 at 2 μg/ml on an Nickel Coated plate can bind Anti-CLDN6/9 recombinant antibody (CSB-RA005508MA1HU). The EC50?is 2.812-3.524 ng/mL.
CLDN9 Antibodies
CLDN9 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA005511GA01HU | CLDN9 Antibody | Human,Mouse,Rat | ELISA,WB |
CLDN9 Proteins
CLDN9 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP005511HU1 CSB-EP005511HU1 CSB-BP005511HU1 CSB-MP005511HU1 CSB-EP005511HU1-B |
Recombinant Human Claudin-9 (CLDN9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005511HU | Recombinant Human Claudin-9 (CLDN9) | in vitro E.coli expression system |
| CSB-MP005511HU | Recombinant Human Claudin-9 (CLDN9)-VLPs (Active) | Mammalian cell |
| CSB-MP005511HU1-D | Recombinant Human Claudin-9 (CLDN9), partial-Detergent (Active) | Mammalian cell |
