CLEC2D
CLEC2D，全稱為C-type lectin domain family 2 member D，常見別名包括CLAX、LLT1、OCIL等。該蛋白主要位于細(xì)胞膜外基質(zhì)，具有抑制破骨細(xì)胞形成、調(diào)節(jié)干擾素-γ釋放、結(jié)合高分子量硫酸化糖胺聚糖等多種功能。CLEC2D蛋白在多種組織中表達(dá)，包括胎兒心臟、腦、肺、軟骨細(xì)胞等，并在成人脾細(xì)胞、胸腺細(xì)胞、淋巴結(jié)細(xì)胞等組織中也有檢測(cè)到。研究表明，CLEC2D蛋白與腫瘤免疫治療密切相關(guān)，其在惡性腦腫瘤中發(fā)揮重要作用。通過(guò)阻斷CLEC2D與CD161受體的相互作用，可以增強(qiáng)T細(xì)胞對(duì)腫瘤細(xì)胞的殺傷作用，提高動(dòng)物的存活率。此外，CLEC2D蛋白還與黑色素瘤、肺癌、結(jié)腸癌和肝癌等多種癌癥相關(guān)。目前，針對(duì)CLEC2D蛋白的藥物研發(fā)正在積極進(jìn)行中，有望為癌癥患者提供新的治療策略。
熱銷產(chǎn)品
CLEC2D Antibody (CSB-PA254797)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA254797(CLEC2D Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA254797(CLEC2D Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)
Human C-type lectin domain family 2 member D(CLEC2D) ELISA kit (CSB-EL005528HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL005528HU
規(guī)格：96T/48T
靈敏度：7.81 pg/mL
檢測(cè)范圍：31.25 pg/mL-2000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CLEC2D Antibodies
CLEC2D for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA254797 | CLEC2D Antibody | Human | ELISA,IHC |
| CSB-PA114834 | CLEC2D Antibody | Human | ELISA,IHC |
| CSB-PA883401LA01HU | CLEC2D Antibody | Human | ELISA |
| CSB-PA883401LB01HU | CLEC2D Antibody, HRP conjugated | Human | ELISA |
| CSB-PA883401LC01HU | CLEC2D Antibody, FITC conjugated | Human | |
| CSB-PA883401LD01HU | CLEC2D Antibody, Biotin conjugated | Human | ELISA |
CLEC2D Proteins
CLEC2D Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP883401HU CSB-EP883401HU CSB-BP883401HU CSB-MP883401HU CSB-EP883401HU-B |
Recombinant Human C-type lectin domain family 2 member D (CLEC2D), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CLEC2D ELISA Kit
CLEC2D ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL005528HU | Human C-type lectin domain family 2 member D(CLEC2D) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 7.81 pg/mL |
