CREBBP
CREBBP，即cAMP反應(yīng)元件結(jié)合蛋白結(jié)合蛋白，別名CBP、RSTS、KAT3A、MKHK1、RSTS1。CREBBP是一種在細(xì)胞核中廣泛表達(dá)的基因，它通過與多種轉(zhuǎn)錄因子相互作用，參與胚胎發(fā)育、生長控制和體內(nèi)平衡等重要生理過程。CREBBP的作用機(jī)制主要體現(xiàn)在其編碼的蛋白質(zhì)上，該蛋白質(zhì)具有組蛋白乙酰轉(zhuǎn)移酶活性，能夠乙?；M蛋白和非組蛋白，從而調(diào)控基因的轉(zhuǎn)錄。此外，CREBBP蛋白還作為支架蛋白，穩(wěn)定與其他蛋白質(zhì)的相互作用，促進(jìn)轉(zhuǎn)錄復(fù)合物的形成。CREBBP對維持細(xì)胞的正常功能和調(diào)控細(xì)胞周期具有重要作用。CREBBP基因的突變可導(dǎo)致Rubinstein-Taybi綜合征（RTS），并且與急性髓性白血病的發(fā)生有關(guān)。
熱銷產(chǎn)品
Recombinant Human CREB-binding protein (CREBBP), partial (CSB-EP838805HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CREBBP Antibody (CSB-PA838805LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA838805LA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA838805LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
CREBBP Antibodies
CREBBP for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA901849 | CREBBP Antibody | Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA000107 | Acetyl-CREBBP (K1535) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA001358 | CREBBP Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA001359 | CREBBP Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA824713 | CREBBP Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA838805LA01HU | CREBBP Antibody | Human | ELISA, IHC, IF |
CREBBP Proteins
CREBBP Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP005954MO CSB-EP005954MO CSB-BP005954MO CSB-MP005954MO CSB-EP005954MO-B |
Recombinant Mouse CREB-binding protein (Crebbp), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CREBBP Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP757128RA CSB-EP757128RA CSB-BP757128RA CSB-MP757128RA CSB-EP757128RA-B |
Recombinant Rat CREB-binding protein (Crebbp), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CREBBP Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP838805HU CSB-EP838805HU CSB-BP838805HU CSB-MP838805HU CSB-EP838805HU-B |
Recombinant Human CREB-binding protein (CREBBP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP838805HU1 | Recombinant Human CREB-binding protein (CREBBP), partial | E.coli |
