CXCL2
CXCL2，全稱C-X-C motif chemokine ligand 2，也被稱為Gro-beta或MIP-2，是一種小分子細(xì)胞因子，屬于CXC趨化因子家族。它主要由活化的單核細(xì)胞、巨噬細(xì)胞和嗜中性粒細(xì)胞產(chǎn)生，并在炎癥部位表達(dá)。CXCL2能夠募集多形核白細(xì)胞和造血干細(xì)胞，對中性粒細(xì)胞具有強(qiáng)大的趨化活性，參與多種免疫反應(yīng)，如傷口愈合、癌癥轉(zhuǎn)移和血管生成等。研究表明，CXCL2在腫瘤微環(huán)境中發(fā)揮著重要作用，它能夠促進(jìn)癌細(xì)胞的增殖、遷移和免疫逃逸，并與多種炎癥性疾病的發(fā)病機(jī)制密切相關(guān)。因此，CXCL2成為腫瘤和炎癥性疾病治療的重要靶點(diǎn)。目前，針對CXCL2/CXCR2軸的藥物研發(fā)已成為熱點(diǎn)，一些CXCR2抑制劑在臨床前模型和早期臨床試驗(yàn)中展現(xiàn)出一定的潛力，為相關(guān)疾病的治療提供了新的思路。
熱銷產(chǎn)品
Recombinant Human C-X-C motif chemokine 2 (CXCL2) (CSB-EP006248HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human macrophage inflammatory protein 2,MIP-2 ELISA Kit (CSB-E07420h)
驗(yàn)證數(shù)據(jù)
貨號：CSB-E07420h
規(guī)格：96T/48T
靈敏度：7.81 pg/mL
檢測范圍：3.12 pg/mL-200 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CXCL2 Antibodies
CXCL2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA08989A0Rb | CXCL2 Antibody | Human | ELISA |
| CSB-PA08989B0Rb | CXCL2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA08989C0Rb | CXCL2 Antibody, FITC conjugated | Human | |
| CSB-PA08989D0Rb | CXCL2 Antibody, Biotin conjugated | Human | ELISA |
CXCL2 Proteins
CXCL2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006248MO CSB-EP006248MO CSB-BP006248MO CSB-MP006248MO CSB-EP006248MO-B |
Recombinant Mouse C-X-C motif chemokine 2 (Cxcl2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP092274m | Recombinant Mouse C-X-C motif chemokine 2 protein (Cxcl2) | E.coli |
| CSB-AP001071MO | Recombinant Mouse C-X-C motif chemokine 2 protein (Cxcl2) | E.Coli |
CXCL2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006248HU CSB-BP006248HU CSB-MP006248HU CSB-EP006248HU-B |
Recombinant Human C-X-C motif chemokine 2 (CXCL2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP000641HU | Recombinant Human C-X-C motif chemokine 2 protein (CXCL2) | E.Coli |
| CSB-AP003541HU | Recombinant Human C-X-C motif chemokine 2 (CXCL2), partial (Active) | E.coli |
| CSB-EP006248HU | Recombinant Human C-X-C motif chemokine 2 (CXCL2) | E.coli |
CXCL2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP006248RA CSB-EP006248RA CSB-BP006248RA CSB-MP006248RA CSB-EP006248RA-B |
Recombinant Rat C-X-C motif chemokine 2 (Cxcl2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001401RA | Recombinant Rat C-X-C motif chemokine 2 protein (Cxcl2), partial (Active) | E.Coli |
CXCL2 ELISA Kit
CXCL2 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04666m | Mouse Macrophage Inflammatory Protein 2,MIP-2 ELISA kit | serum, plasma, tissue homogenates | 5.8 pg/mL |
CXCL2 ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07419r | Rat macrophage inflammatory protein 2,MIP-2 ELISA kit | serum, plasma, tissue homogenates | 19.5 pg/mL |
CXCL2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07420h | Human macrophage inflammatory protein 2,MIP-2 ELISA Kit | serum, plasma, cell culture supernates, urine | 7.81 pg/mL |
