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DERL1

Derlin-1 is a protein in humans that is encoded by DERL1 gene. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded protein

DERL1 Proteins

DERL1 Proteins for Dictyostelium discoideum (Slime mold)

DERL1 Proteins for Pongo abelii (Sumatran orangutan)

DERL1 Proteins for Bos taurus (Bovine)

DERL1 Proteins for Mus musculus (Mouse)

DERL1 Proteins for Homo sapiens (Human)