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DHCR7

DHCR7,全稱為7-脫氫膽固醇還原酶,是一種重要的酶,負(fù)責(zé)將7-脫氫膽固醇轉(zhuǎn)化為膽固醇。該蛋白有多種別名,如7-DHC還原酶、DHCR7抗體等。它在細(xì)胞膜中發(fā)揮關(guān)鍵作用,參與膽固醇的代謝。DHCR7的異??赡軐?dǎo)致Smith-Lemli-Opitz綜合征(SLOS),這是一種影響膽固醇代謝的遺傳疾病,患者可能出現(xiàn)認(rèn)知障礙、面部畸形等癥狀。近年來,研究人員發(fā)現(xiàn)DHCR7在抗病毒感染中也扮演重要角色,因此,針對DHCR7的藥物研發(fā)成為研究熱點(diǎn)。目前,已有一些研究探索了DHCR7抑制劑在治療病毒感染中的應(yīng)用潛力。

熱銷產(chǎn)品

DHCR7 Antibody (CSB-PA006844LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA006844LA01HU

Western Blot
Positive WB detected in: HepG2 whole cell lysate, Hela whole cell lysate, MCF-7 whole cell lysate
All lanes: DHCR7 antibody at 2.4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 55 kDa
Observed band size: 55 kDa

CSB-PA006844LA01HU

IHC image of CSB-PA006844LA01HU diluted at 1:600 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

DHCR7 Antibodies

DHCR7 for Homo sapiens (Human)

DHCR7 Proteins

DHCR7 Proteins for Homo sapiens (Human)