DLL4
DLL4，全稱為Delta-like protein 4。它在Notch信號(hào)通路中扮演重要角色，作為Notch配體激活NOTCH1和NOTCH4，參與細(xì)胞通信和血管生成調(diào)控。DLL4蛋白與多種疾病相關(guān)，如上皮性卵巢癌等。在藥物研發(fā)方面，DLL4蛋白已成為抗腫瘤治療的新靶點(diǎn)，相關(guān)雙抗藥物如VEGF/DLL4雙抗在臨床試驗(yàn)中取得顯著進(jìn)展，有望成為膽道癌二線治療的新標(biāo)準(zhǔn)。
熱銷產(chǎn)品
Recombinant Human Delta-like protein 4 (DLL4),partial (Active) (CSB-MP878862HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human DLL4 at 2 μg/ml can bind Anti-DLL4 recombinant antibody (CSB-RA878862MA1HU). The EC50 is 2.322-2.607 ng/mL.
DLL4 (Navicixizumab) Recombinant Monoclonal Antibody (CSB-RA878862MA1HU)
驗(yàn)證數(shù)據(jù)
The Binding Activity of Human DLL4 with Anti-DLL4 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DLL4 (CSB-MP878862HU) at 2 μg/mL can bind Anti-DLL4 recombinant antibody . The EC50 is 2.322-2.607 ng/mL.
DLL4 Antibodies
DLL4 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA073786 | DLL4 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA831848 | DLL4 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA006949LA01HU | DLL4 Antibody | Human | ELISA, IF |
| CSB-PA006949LB01HU | DLL4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA006949LC01HU | DLL4 Antibody, FITC conjugated | Human | |
| CSB-PA006949LD01HU | DLL4 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA878862MA1HU | DLL4 (Navicixizumab) Recombinant Monoclonal Antibody | Human | ELISA |
DLL4 Proteins
DLL4 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP347231XBE CSB-EP347231XBE CSB-BP347231XBE CSB-MP347231XBE CSB-EP347231XBE-B |
Recombinant Xenopus laevis Homeobox protein DLL-4 (dll4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL4 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP867483MO CSB-EP867483MO CSB-BP867483MO CSB-MP867483MO CSB-EP867483MO-B |
Recombinant Mouse Delta-like protein 4 (Dll4), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL4 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP878862HU CSB-EP878862HU CSB-BP878862HU CSB-EP878862HU-B |
Recombinant Human Delta-like protein 4 (DLL4), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP878862HU | Recombinant Human Delta-like protein 4 (DLL4),partial (Active) | Mammalian cell |
DLL4 ELISA Kit
DLL4 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL006949HU | Human Delta-like protein 4(DLL4) ELISA kit | serum, plasma, tissue homogenates | 5.8 pg/mL |
DLL4 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL006949MO | Mouse Delta-like protein 4(DLL4) ELISA kit | serum, plasma, tissue homogenates | 0.04 ng/mL |
