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E6

E6指的通常是HPV(人乳頭瘤病毒)蛋白,它具有致癌作用。HPV的E6蛋白有多種亞型,但通常具有兩個關(guān)鍵特征:一個是與宿主細(xì)胞中的特定蛋白質(zhì)(比如細(xì)胞周期調(diào)控相關(guān)的蛋白)結(jié)合的能力;另一個是對細(xì)胞中某些蛋白的降解能力。 E6蛋白與宿主細(xì)胞中的特定蛋白質(zhì)結(jié)合,比如p53蛋白,這通常導(dǎo)致這些蛋白的降解。當(dāng)E6蛋白與p53結(jié)合并導(dǎo)致其降解時,細(xì)胞失去了對異常細(xì)胞生長的控制機(jī)制,有可能導(dǎo)致細(xì)胞不受控制地增殖。對E6蛋白的研究在了解HPV感染導(dǎo)致的癌癥發(fā)生機(jī)制、腫瘤形成以及癌癥治療方面非常重要。這種了解可以幫助開發(fā)針對HPV相關(guān)癌癥的預(yù)防和治療方法,同時也有助于深入了解癌癥發(fā)展的過程。

熱銷產(chǎn)品

Recombinant Human papillomavirus type 16 Protein E6 (E6)

驗(yàn)證數(shù)據(jù)

SDS-PAGE
CSB-EP365854HML-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

LC-MS
CSB-EP365854HML LC-MS-1

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS Analysis result of CSB-EP365854HML could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) E6.

LC-MS
CSB-EP365854HML LC-MS-2

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS Analysis result of CSB-EP365854HML could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) E6.


E6 Antibodies

E6 for Human papillomavirus type 16

E6 Proteins

E6 Proteins for Human papillomavirus type 16

E6 Proteins for Homo sapiens (Human)