ELANE
ELANE,全稱為彈性蛋白酶,中性粒細(xì)胞表達(dá),也被稱為中性粒細(xì)胞彈性蛋白酶。這是一種絲氨酸蛋白酶,主要在中性粒細(xì)胞中表達(dá)。它能夠水解多種蛋白質(zhì),除了彈性蛋白外,還能降解細(xì)菌的外膜蛋白,如大腸桿菌的OmpA。ELANE在退行性和炎癥性疾病中可能發(fā)揮作用,其突變與周期性中性粒細(xì)胞減少癥和嚴(yán)重的先天性中性粒細(xì)胞減少癥相關(guān)。在藥物研發(fā)方面,ELANE蛋白及其相關(guān)疾病的研究為開發(fā)新的治療策略提供了新的方向。
熱銷產(chǎn)品
Recombinant Human Neutrophil elastase (ELANE) (CSB-EP007587HUe1)
驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ELANE Recombinant Monoclonal Antibody (CSB-RA200985A0HU)
驗(yàn)證數(shù)據(jù)

IHC image of CSB-RA200985A0HU diluted at 1:100 and staining in paraffin-embedded human spleen tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Overlay histogram showing Jurkat cells stained with CSB-RA200985A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.
ELANE Antibodies
ELANE for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA007587LA01HU | ELANE Antibody | Human | ELISA, IHC, IF |
CSB-PA007587LB01HU | ELANE Antibody, HRP conjugated | Human | ELISA |
CSB-PA007587LC01HU | ELANE Antibody, FITC conjugated | Human | |
CSB-PA007587LD01HU | ELANE Antibody, Biotin conjugated | Human | ELISA |
CSB-RA200985A0HU | ELANE Recombinant Monoclonal Antibody | Human | ELISA, IHC, FC |
ELANE Proteins
ELANE Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP007587HU | Recombinant Human Neutrophil elastase (ELANE) | Yeast |
CSB-EP007587HU | Recombinant Human Neutrophil elastase (ELANE) | E.coli |
Recombinant Human Neutrophil elastase (ELANE) | ||
CSB-EP007587HU-B | Recombinant Human Neutrophil elastase (ELANE),Biotinylated | E.coli |
CSB-EP007587HUe1 | Recombinant Human Neutrophil elastase (ELANE) | E.coli |
CSB-EP007587HUb0 | Recombinant Human Neutrophil elastase (ELANE) | E.coli |
CSB-EP007587HUc7 | Recombinant Human Neutrophil elastase (ELANE) | E.coli |
CSB-MP007587HU | Recombinant Human Neutrophil elastase (ELANE) | Mammalian cell |
CSB-BP007587HU | Recombinant Human Neutrophil elastase (ELANE) | Baculovirus |
CSB-MP007587HU1 | Recombinant Human Neutrophil elastase (ELANE), partial | Mammalian cell |
ELANE Proteins for Mus musculus (Mouse)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP659740MO CSB-EP659740MO CSB-BP659740MO CSB-MP659740MO CSB-EP659740MO-B |
Recombinant Mouse Neutrophil elastase (Elane) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ELANE ELISA Kit
ELANE ELISA Kit for Mus musculus (Mouse)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-E04804m | Mouse neutrophil elastase,NE ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 0.078 ng/mL |
ELANE ELISA Kit for Rattus norvegicus (Rat)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-E08847r | Rat neutrophil elastase,NE ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates, cell lysates | 3.12 ng/mL |
ELANE ELISA Kit for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-EL007587HU | Human elastase 2, neutrophil (ELA2)ELISA kit | serum, plasma, tissue homogenates | 1.56 ng/mL |