EZH1
EZH1，即增強(qiáng)子蛋白鋅指同源物1，別名人類EZH2相關(guān)蛋白、KIAA0999。它是一種由EZH1基因編碼的酶，屬于多梳蛋白復(fù)合體PRC2（Polycomb Repressive Complex 2）的催化亞基。EZH1的作用機(jī)制主要通過催化組蛋白H3第27位賴氨酸的甲基化，形成H3K27me3，從而抑制特定基因的表達(dá)。EZH1在細(xì)胞增殖、分化、發(fā)育和腫瘤發(fā)生等生物學(xué)過程中發(fā)揮重要作用。其異常表達(dá)與多種癌癥的發(fā)生發(fā)展密切相關(guān)，是癌癥治療的潛在靶點(diǎn)。
熱銷產(chǎn)品
EZH1 Antibody (CSB-PA852913DSR2HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: Histone-lysine N-methyltransferase EZH1 antibody at 4μg/ml
Lane 1: Hela whole cell lysate
Lane 2: HL60 whole cell lysate
Lane 3: Mouse gonad tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 86, 87, 81, 77, 69 kDa
Observed band size: 86 kDa
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA852913DSR2HU at dilution of 1:100
EZH1 Antibodies
EZH1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007912GA01HU | EZH1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA852913DSR1HU | EZH1 Antibody | Human | ELISA, IHC |
| CSB-PA852913DSR2HU | EZH1 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA002349 | EZH1 Antibody | Human,Mouse,Monkey | WB, IHC, IF, ELISA |
| CSB-PA852913DA01HU | EZH1 Antibody | Human | ELISA, IHC |
EZH1 Proteins
EZH1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP852913HU CSB-EP852913HU CSB-BP852913HU CSB-MP852913HU CSB-EP852913HU-B |
Recombinant Human Histone-lysine N-methyltransferase EZH1 (EZH1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
