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FASLG

FASLG,全稱為Fas配體(Fas ligand),常見別名為CD178、APT1LG1等。該蛋白屬于腫瘤壞死因子超家族成員,主要功能是誘導細胞凋亡。FASLG通過與FAS受體結合,觸發(fā)細胞凋亡信號轉導途徑,在免疫系統(tǒng)的調節(jié)中發(fā)揮重要作用,例如T細胞的活化誘導細胞死亡(AICD)和細胞毒性T淋巴細胞誘導的細胞死亡。FASLG的表達異常與多種疾病相關,包括自身免疫性淋巴細胞增生性綜合征、系統(tǒng)性紅斑狼瘡、糖尿病、心肌病、動脈粥樣硬化和非小細胞肺癌等。目前,針對FASLG的藥物研發(fā)主要集中在免疫調節(jié)和抗腫瘤領域。例如,一些研究表明,F(xiàn)ASLG抑制劑可以用于治療自身免疫性疾病,而FASLG激活劑則可能用于增強抗腫瘤免疫反應。此外,F(xiàn)ASLG也被用作生物標志物,用于評估疾病的進展和治療效果。隨著對FASLG蛋白功能的深入研究,未來有望開發(fā)出更多針對FASLG的藥物,用于治療多種疾病。

熱銷產品

Recombinant Human Tumor necrosis factor ligand superfamily member 6 (FASLG), partial (CSB-YP008434HU)

驗證數(shù)據(jù)

CSB-YP008434HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FASLG Antibody (CSB-PA008434LA01HU)

驗證數(shù)據(jù)

CSB-PA008434LA01HU

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA008434LA01HU at dilution of 1:100

CSB-PA008434LA01HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA008434LA01HU at dilution of 1:100

CSB-PA008434LA01HU

Immunofluorescence staining of Hela cells with CSB-PA008434LA01HU at 1:330, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Human Factor-related Apoptosis ligand,FASL ELISA Kit (CSB-E04544h)

驗證數(shù)據(jù)

CSB-E04544h 標準曲線

貨號:CSB-E04544h

規(guī)格:96T/48T

靈敏度:7.81 pg/mL

檢測范圍:31.25 pg/mL-2000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

FASLG Antibodies

FASLG for Homo sapiens (Human)

FASLG Proteins

FASLG Proteins for Mus musculus (Mouse)

FASLG Proteins for Rattus norvegicus (Rat)

FASLG Proteins for Homo sapiens (Human)

FASLG Proteins for Macaca mulatta (Rhesus macaque)

FASLG Proteins for Macaca nemestrina (Pig-tailed macaque)

FASLG Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

FASLG Proteins for Felis catus (Cat) (Felis silvestris catus)

FASLG Proteins for Sus scrofa (Pig)

FASLG Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

FASLG ELISA Kit

FASLG ELISA Kit for Homo sapiens (Human)

FASLG ELISA Kit for Mus musculus (Mouse)

FASLG ELISA Kit for Rattus norvegicus (Rat)