FOLR2
FOLR2,全稱為葉酸受體β(Folate Receptor Beta),也被稱為FBP、FOLR2、BETA-HFR、FBP/PL-1、FR-BETA、FR-P3和FR-P4。該蛋白屬于葉酸受體(FOLR)家族,主要存在于胎盤、中性粒細胞譜系細胞和部分CD34+造血祖細胞中。FOLR2蛋白原本被認為僅存在于胎盤中,但后來發(fā)現(xiàn)也存在于脾臟、骨髓和胸腺。它在惡性腫瘤、頭頸鱗狀細胞癌和多種非上皮性癌癥中表達上調(diào),尤其是在單核細胞和巨噬細胞中。FOLR2蛋白是M-CSF生成的巨噬細胞的標志物,其表達與葉酸攝取能力的增加相關(guān)。葉酸綴合的藥物是靶向腫瘤相關(guān)巨噬細胞的潛在免疫療法工具。
熱銷產(chǎn)品
Recombinant Human Folate receptor beta (FOLR2), partial (CSB-BP008786HU1)
驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
FOLR2 Antibody (CSB-PA008786LA01HU)
驗證數(shù)據(jù)

IHC image of CSB-PA008786LA01HU diluted at 1:400 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of Hela cells with CSB-PA008786LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
FOLR2 Antibodies
FOLR2 for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA008786LA01HU | FOLR2 Antibody | Human | ELISA, IHC, IF |
CSB-PA008786LB01HU | FOLR2 Antibody, HRP conjugated | Human | ELISA |
CSB-PA008786LC01HU | FOLR2 Antibody, FITC conjugated | Human | |
CSB-PA008786LD01HU | FOLR2 Antibody, Biotin conjugated | Human | ELISA |
FOLR2 Proteins
FOLR2 Proteins for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP008786HU CSB-EP008786HU CSB-BP008786HU CSB-MP008786HU CSB-EP008786HU-B |
Recombinant Human Folate receptor beta (FOLR2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-BP008786HU1 | Recombinant Human Folate receptor beta (FOLR2), partial | Baculovirus |