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FXR1

FXR1,即FMR1常染色體同系物1,別名FMR1 Autosomal Homolog 1、Fragile X Mental Retardation Syndrome-Related Protein 1、HFXR1p、FXR1P。FXR1是一種RNA結(jié)合蛋白,與功能相似的FMR1和FXR2相互作用。這些蛋白質(zhì)在細(xì)胞核和細(xì)胞質(zhì)之間穿梭,并與多聚核糖體結(jié)合,主要與60S核糖體亞基結(jié)合。FXR1通過其RNA結(jié)合能力以及與其他蛋白質(zhì)的相互作用,參與調(diào)控基因表達(dá)和mRNA的穩(wěn)定性。FXR1在多種細(xì)胞過程中發(fā)揮作用,包括細(xì)胞增殖、分化和腫瘤發(fā)生。FXR1的異常表達(dá)與多種疾病相關(guān),包括某些類型的癌癥和神經(jīng)退行性疾病。

熱銷產(chǎn)品

Recombinant Human Fragile X mental retardation syndrome-related protein 1 (FXR1), partial (CSB-EP009087HU5)

驗(yàn)證數(shù)據(jù)

CSB-EP009087HU5

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FXR1 Antibody (CSB-PA009087LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA009087LA01HU

Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate, NIH/3T3 whole cell lysate
All lanes: FXR1 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 70, 61, 60 kDa
Observed band size: 70 kDa

CSB-PA009087LA01HU

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA009087LA01HU at dilution of 1:100

CSB-PA009087LA01HU

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA009087LA01HU at dilution of 1:100

CSB-PA009087LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA009087LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

FXR1 Antibodies

FXR1 for Homo sapiens (Human)