G6PD
G6PD，即葡萄糖-6-磷酸脫氫酶。別名G-6-PD，它是一種位于紅細(xì)胞中的酶，主要功能是催化磷酸戊糖途徑的第一步反應(yīng)，產(chǎn)生還原型輔酶Ⅱ(NADPH)，這種酶對于維持紅細(xì)胞膜的完整性和保護(hù)血紅蛋白免受氧化損傷至關(guān)重要。G6PD缺乏會(huì)導(dǎo)致紅細(xì)胞在遇到某些藥物、食物（如蠶豆）或感染時(shí)，無法有效抵抗氧化應(yīng)激，從而導(dǎo)致紅細(xì)胞破裂和溶血。G6PD基因位于X染色體上，因此該缺乏癥是一種X連鎖遺傳病，男性患者多于女性。全球約有4億人患有G6PD缺乏癥，尤其在地中海地區(qū)、非洲、東南亞和中國南方地區(qū)較為常見。臨床上，G6PD缺乏癥的表現(xiàn)為溶血性貧血，癥狀包括黃疸、蒼白、深色尿液和腹痛等。
熱銷產(chǎn)品
Recombinant Human Glucose-6-phosphate 1-dehydrogenase (G6PD) (CSB-YP009121HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
G6PD Antibody (CSB-PA009121LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA009121LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA009121LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
G6PD Antibodies
G6PD for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA009121KA01HU | G6PD Antibody | Human,Mouse | ELISA,WB |
| CSB-PA009121LA01HU | G6PD Antibody | Human | ELISA, IHC, IF |
| CSB-PA009121LB01HU | G6PD Antibody, HRP conjugated | Human | ELISA |
| CSB-PA009121LC01HU | G6PD Antibody, FITC conjugated | Human | |
| CSB-PA009121LD01HU | G6PD Antibody, Biotin conjugated | Human | ELISA |
G6PD Proteins
G6PD Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP009121HU CSB-BP009121HU CSB-MP009121HU CSB-EP009121HU-B |
Recombinant Human Glucose-6-phosphate 1-dehydrogenase (G6PD) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP009121HU | Recombinant Human Glucose-6-phosphate 1-dehydrogenase (G6PD) | Yeast |
