GDF2

GDF2，即生長分化因子2，別名BMP-9、BMP9，屬于轉(zhuǎn)化生長因子β超家族（TGF-beta superfamily）中的BMP亞群成員。GDF2主要通過與ALK1等受體結(jié)合，傳遞信號，從而調(diào)節(jié)多種胚胎和成體組織的發(fā)育和功能。GDF2的作用機制涉及與ALK1等受體的結(jié)合，激活下游的Smad蛋白，進而影響基因表達。GDF2在肝臟非實質(zhì)細胞中合成分泌，能夠促進脂質(zhì)代謝并抑制葡萄糖生成。它在胚胎中樞神經(jīng)系統(tǒng)中對膽堿能神經(jīng)元表型的發(fā)育和維持起著重要作用，同時也誘導間充質(zhì)干細胞分化為軟骨細胞系。GDF2的功能還包括調(diào)節(jié)血管生成、影響內(nèi)皮細胞增殖以及參與骨骼和軟骨的發(fā)育。GDF2的異常表達與遺傳性出血性毛細血管擴張癥相關。

熱銷產(chǎn)品

Recombinant Human Growth/differentiation factor 2 (GDF2) (CSB-EP892325HU1)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GDF2 Antibody (CSB-PA892325LA01HU)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA892325LA01HU at dilution of 1:100

GDF2 Antibody

GDF2 Protein

GDF2 ELISA Kit

GDF2 Antibodies

GDF2 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應性	應用類型
CSB-PA892325GA01HU	GDF2 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA886231	GDF2 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA356766	GDF2 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA892325LA01HU	GDF2 Antibody	Human	ELISA, IHC
CSB-PA892325LD01HU	GDF2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA892325LC01HU	GDF2 Antibody, FITC conjugated	Human
CSB-PA892325LB01HU	GDF2 Antibody, HRP conjugated	Human	ELISA

GDF2 Proteins

GDF2 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP892325HU1	Recombinant Human Growth/differentiation factor 2 (GDF2), partial	Yeast
CSB-EP892325HU1	Recombinant Human Growth/differentiation factor 2 (GDF2)	E.coli