GHR
生長(zhǎng)激素-不僅僅促進(jìn)長(zhǎng)高
生長(zhǎng)激素結(jié)合蛋白（growth hormone binding protein，GHBP）是血液中生長(zhǎng)激素（GH）的運(yùn)輸?shù)鞍祝碇L(zhǎng)激素受體（GHR）的膜外部分，反應(yīng)了組織GHR的濃度，對(duì)GH生物學(xué)作用的發(fā)揮起著重要的作用。GHBP作為生長(zhǎng)素活性調(diào)節(jié)劑，進(jìn)入血液循環(huán)的GH幾乎都與高親和力的GHBP結(jié)合在一起，刺激靶器官產(chǎn)生類胰島素生長(zhǎng)因子-1（insulin-like growth factor-1，IGF-1），GHBP再與IGF-1受體結(jié)合發(fā)揮作用，生長(zhǎng)激素與IGF-1的這種關(guān)系也叫做生長(zhǎng)激素/IGF-1軸。因此，GHBP是了解生長(zhǎng)激素—胰島素樣生長(zhǎng)因子（GH-IGF-1）軸變化的主要指標(biāo)。研究發(fā)現(xiàn)血GHBP水平下降，可能與GH抵抗綜合征有關(guān)，如肝硬化、腎功能不全、糖尿病、甲狀腺功能減退癥、營(yíng)養(yǎng)不良癥和重癥急性疾病等等。
Recombinant Human GHR 活性蛋白實(shí)驗(yàn)驗(yàn)證數(shù)據(jù)
by SDS-PAGE
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Measured by its binding ability in a functional ELISA. Immobilized GH1 (CSB-MP009407HU) at 1 μg/ml can bind human GHR, the EC50 of human GHR protein is 24.96-33.39 ng/ml.
Human GH1 protein his/myc tag (CSB-MP009407HU) captured on COOH chip can bind Human GHR protein Fc tag (CSB-MP009411HU) with an affinity constant of 6.1 nM as detected by LSPR Assay.
GHR Antibodies
GHR for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006152 | GHR Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA278805 | GHR Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA381442 | GHR Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA009411LA01HU | GHR Antibody | Human | ELISA, IHC |
| CSB-PA009411LB01HU | GHR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA009411LC01HU | GHR Antibody, FITC conjugated | Human | |
| CSB-PA009411LD01HU | GHR Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA978909A0HU | GHR Recombinant Monoclonal Antibody | Human | ELISA, IHC, IF |
GHR Proteins
GHR Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411MOW CSB-BP009411MOW CSB-MP009411MOW CSB-EP009411MOW-B |
Recombinant Macaca mulatta Growth hormone receptor (GHR), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009411MOW(A4) | Recombinant Macaca mulatta Growth hormone receptor (GHR) | in vitro E.coli expression system |
| CSB-EP009411MOW | Recombinant Macaca mulatta Growth hormone receptor (GHR), partial | E.coli |
GHR Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411CH1 CSB-EP009411CH1 CSB-BP009411CH1 CSB-MP009411CH1 CSB-EP009411CH1-B |
Recombinant Chicken Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009411CH | Recombinant Chicken Growth hormone receptor (GHR) | in vitro E.coli expression system |
GHR Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411HU CSB-BP009411HU CSB-EP009411HU-B |
Recombinant Human Growth hormone receptor (GHR), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF009411HU | Recombinant Human Growth hormone receptor (GHR) | in vitro E.coli expression system |
| CSB-EP009411HU | Recombinant Human Growth hormone receptor (GHR), partial | E.coli |
| CSB-MP009411HU | Recombinant Human Growth hormone receptor (GHR), partial (Active) | Mammalian cell |
| CSB-MP009411HUj1-B | Recombinant Human Growth hormone receptor (GHR), partial,Biotinylated (Active) | Mammalian cell |
GHR Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411PI1 CSB-EP009411PI1 CSB-BP009411PI1 CSB-MP009411PI1 CSB-EP009411PI1-B |
Recombinant Pig Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009411PI | Recombinant Pig Growth hormone receptor (GHR) | in vitro E.coli expression system |
| CSB-EP009411PI | Recombinant Pig Growth hormone receptor (GHR), partial | E.coli |
GHR Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411RB1 CSB-EP009411RB1 CSB-BP009411RB1 CSB-MP009411RB1 CSB-EP009411RB1-B |
Recombinant Rabbit Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009411RB | Recombinant Rabbit Growth hormone receptor (GHR) | in vitro E.coli expression system |
| CSB-CF009411RB1 | Recombinant Rabbit Growth hormone receptor (GHR), partial | in vitro E.coli expression system |
GHR Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411MO1 CSB-EP009411MO1 CSB-BP009411MO1 CSB-MP009411MO1 CSB-EP009411MO1-B |
Recombinant Mouse Growth hormone receptor (Ghr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009411MO | Recombinant Mouse Growth hormone receptor (Ghr) | in vitro E.coli expression system |
GHR Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411BO1 CSB-EP009411BO1 CSB-BP009411BO1 CSB-MP009411BO1 CSB-EP009411BO1-B |
Recombinant Bovine Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009411BO | Recombinant Bovine Growth hormone receptor (GHR) | in vitro E.coli expression system |
GHR Proteins for Bos indicus (Zebu)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411BUL1 CSB-EP009411BUL1 CSB-BP009411BUL1 CSB-MP009411BUL1 CSB-EP009411BUL1-B |
Recombinant Bos indicus Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009411BUL | Recombinant Bos indicus Growth hormone receptor (GHR) | in vitro E.coli expression system |
GHR Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411RA1 CSB-EP009411RA1 CSB-BP009411RA1 CSB-MP009411RA1 CSB-EP009411RA1-B |
Recombinant Rat Growth hormone receptor (Ghr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009411RA | Recombinant Rat Growth hormone receptor (Ghr) | in vitro E.coli expression system |
GHR Proteins for Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411SWC CSB-EP009411SWC CSB-BP009411SWC CSB-MP009411SWC CSB-EP009411SWC-B |
Recombinant Saimiri boliviensis boliviensis Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GHR Proteins for Ailuropoda melanoleuca (Giant panda)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411AYX CSB-EP009411AYX CSB-BP009411AYX CSB-MP009411AYX CSB-EP009411AYX-B |
Recombinant Ailuropoda melanoleuca Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GHR Proteins for Columba livia (Domestic pigeon)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411DVK CSB-EP009411DVK CSB-BP009411DVK CSB-MP009411DVK CSB-EP009411DVK-B |
Recombinant Columba livia Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GHR Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411DO CSB-BP009411DO CSB-MP009411DO CSB-EP009411DO-B |
Recombinant Dog Growth hormone receptor (GHR), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GHR Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411GU CSB-EP009411GU CSB-BP009411GU CSB-MP009411GU CSB-EP009411GU-B |
Recombinant Guinea pig Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GHR Proteins for Papio anubis (Olive baboon)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411ERI CSB-EP009411ERI CSB-BP009411ERI CSB-MP009411ERI CSB-EP009411ERI-B |
Recombinant Papio anubis Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
GHR Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP009411SH CSB-EP009411SH CSB-BP009411SH CSB-MP009411SH CSB-EP009411SH-B |
Recombinant Sheep Growth hormone receptor (GHR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
