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GIT1

ARF GTPase-activating protein GIT1 is a protein in humans that is encoded by GIT1 gene. GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).

GIT1 Antibodies

GIT1 for Homo sapiens (Human)

GIT1 Proteins

GIT1 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

GIT1 Proteins for Mus musculus (Mouse)

GIT1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)