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GPR55

GPR55,即G蛋白偶聯(lián)受體55,別名LPI1、GPR55、PSIGPR53。GPR55由人類GPR55基因編碼,該基因位于2號(hào)染色體的q37.1區(qū)域。GPR55是一種G蛋白偶聯(lián)受體,可能通過激活多種信號(hào)轉(zhuǎn)導(dǎo)通路參與多種生理和病理過程。它被激活的配體包括植物性大麻素、內(nèi)源性大麻素以及溶血磷脂酰肌醇(LPI)。GPR55與情緒、運(yùn)動(dòng)、認(rèn)知、學(xué)習(xí)和記憶等生理功能相關(guān),同時(shí)也與大麻素的作用以及藥物濫用有關(guān)。GPR55還可能成為治療炎癥、疼痛、糖尿病、帕金森病、神經(jīng)病理性疼痛和癌癥的新潛在藥物靶點(diǎn)。研究表明,GPR55在調(diào)節(jié)焦慮樣行為、海馬神經(jīng)發(fā)生以及神經(jīng)保護(hù)方面發(fā)揮作用。

熱銷產(chǎn)品

GPR55 Antibody (CSB-PA009820OA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA009820OA01HU

IHC image of CSB-PA009820OA01HU diluted at 1:100 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

GPR55 Antibodies

GPR55 for Homo sapiens (Human)

GPR55 Proteins

GPR55 Proteins for Mus musculus (Mouse)