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GZMK

GZMK,即顆粒酶M,別名Granzyme K、Gzmk。它是一種由GZMK基因編碼的絲氨酸蛋白酶,屬于顆粒酶家族成員,在細(xì)胞毒性T淋巴細(xì)胞(CTL)和自然殺傷(NK)細(xì)胞中表達(dá)。GZMK的作用機(jī)制涉及與細(xì)胞毒性顆粒中的其他顆粒酶協(xié)同作用,通過誘導(dǎo)靶細(xì)胞凋亡來發(fā)揮其細(xì)胞毒性作用,參與免疫應(yīng)答過程。GZMK的表達(dá)和活性在某些疾病中可能發(fā)生改變,例如在自身免疫性疾病和腫瘤中。因此,GZMK是免疫學(xué)研究和相關(guān)疾病治療中的一個(gè)潛在靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Granzyme K (GZMK) (CSB-EP010084HU)

驗(yàn)證數(shù)據(jù)

CSB-EP010084HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

GZMK Antibody (CSB-PA010084LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA010084LA01HU

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA010084LA01HU at dilution of 1:100

CSB-PA010084LA01HU

Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA010084LA01HU at dilution of 1:100

CSB-PA010084LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA010084LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

GZMK Antibodies

GZMK for Homo sapiens (Human)

GZMK Proteins

GZMK Proteins for Homo sapiens (Human)