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HLA-E

HLA-E,全稱為人類白細(xì)胞抗原E,也被稱為QA1、MHC class I antigen E、HLAE、HLA-6.2、HLA E。它是一種非經(jīng)典的主要組織相容性復(fù)合物I類分子,主要在腫瘤細(xì)胞和病毒感染細(xì)胞中表達(dá)。HLA-E通過與自然殺傷細(xì)胞和T細(xì)胞上的CD94/NKG2A受體結(jié)合,抑制免疫細(xì)胞的殺傷活性,從而幫助腫瘤細(xì)胞逃避免疫系統(tǒng)的監(jiān)視。此外,HLA-E還與某些自身免疫性疾病有關(guān),如強(qiáng)直性脊柱炎、白塞綜合征等。在藥物研發(fā)方面,針對(duì)HLA-E的抗體和融合蛋白正在被開發(fā),以增強(qiáng)免疫治療效果。

熱銷產(chǎn)品

Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E), partial (CSB-EP320269HU)

驗(yàn)證數(shù)據(jù)

CSB-EP320269HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Human major histocompatibility complex, class I, E (HLA-E) ELISA kit (CSB-EL010507HU)

驗(yàn)證數(shù)據(jù)

CSB-EL010507HU 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-EL010507HU

規(guī)格:96T/48T

靈敏度:7.81 pg/mL

檢測(cè)范圍:31.25 pg/mL-2000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

HLA-E Antibodies

HLA-E for Homo sapiens (Human)

HLA-E Proteins

HLA-E Proteins for Homo sapiens (Human)

HLA-E ELISA Kit

HLA-E ELISA Kit for Homo sapiens (Human)