HLA-E
HLA-E,全稱為人類白細(xì)胞抗原E,也被稱為QA1、MHC class I antigen E、HLAE、HLA-6.2、HLA E。它是一種非經(jīng)典的主要組織相容性復(fù)合物I類分子,主要在腫瘤細(xì)胞和病毒感染細(xì)胞中表達(dá)。HLA-E通過與自然殺傷細(xì)胞和T細(xì)胞上的CD94/NKG2A受體結(jié)合,抑制免疫細(xì)胞的殺傷活性,從而幫助腫瘤細(xì)胞逃避免疫系統(tǒng)的監(jiān)視。此外,HLA-E還與某些自身免疫性疾病有關(guān),如強(qiáng)直性脊柱炎、白塞綜合征等。在藥物研發(fā)方面,針對(duì)HLA-E的抗體和融合蛋白正在被開發(fā),以增強(qiáng)免疫治療效果。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human major histocompatibility complex, class I, E (HLA-E) ELISA kit (CSB-EL010507HU)
驗(yàn)證數(shù)據(jù)

貨號(hào):CSB-EL010507HU
規(guī)格:96T/48T
靈敏度:7.81 pg/mL
檢測(cè)范圍:31.25 pg/mL-2000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
HLA-E Antibodies
HLA-E for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA320269LA01HU | HLA-E Antibody | Human | ELISA |
CSB-PA320269LB01HU | HLA-E Antibody, HRP conjugated | Human | ELISA |
CSB-PA320269LC01HU | HLA-E Antibody, FITC conjugated | Human | |
CSB-PA320269LD01HU | HLA-E Antibody, Biotin conjugated | Human | ELISA |
HLA-E Proteins
HLA-E Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP320269HU CSB-MP320269HU CSB-EP320269HU-B |
Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E), partial | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP320269HU | Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E), partial | E.coli |
CSB-BP320269HU | Recombinant Human HLA class I histocompatibility antigen, alpha chain E (HLA-E), partial | Baculovirus |
HLA-E ELISA Kit
HLA-E ELISA Kit for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-EL010507HU | Human major histocompatibility complex, class I, E (HLA-E) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 7.81 pg/mL |