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HP

HP,即結(jié)合珠蛋白(Haptoglobin),是一種由肝臟合成的血漿糖蛋白。它通過(guò)與血紅蛋白結(jié)合,形成穩(wěn)定的復(fù)合物,減少血紅蛋白在血管中的分解,防止鐵離子和血紅素的毒性作用,同時(shí)促進(jìn)血紅蛋白的清除和鐵的循環(huán)利用。HP的作用機(jī)制包括抑制補(bǔ)體激活,減少炎癥反應(yīng),并在免疫調(diào)節(jié)中發(fā)揮作用。生物學(xué)意義上,HP有助于保護(hù)機(jī)體免受溶血后產(chǎn)生的有害物質(zhì)的影響,維持鐵平衡,其基因多態(tài)性與多種疾病包括心血管疾病和腎臟疾病的風(fēng)險(xiǎn)有關(guān),是重要的生物標(biāo)志物,對(duì)臨床診斷和治療有指導(dǎo)作用。

熱銷產(chǎn)品

Recombinant Mouse Haptoglobin (Hp)

驗(yàn)證數(shù)據(jù)

SDS
CSB-EP010691MO SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

HP Recombinant Monoclonal Antibody

驗(yàn)證數(shù)據(jù)

IHC
CSB-RA224179A0HU IHC-1

IHC image of CSB-RA224179A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

IHC
CSB-RA224179A0HU IHC-2

IHC image of CSB-RA224179A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.


HP Antibodies

HP for Homo sapiens (Human)

HP Proteins

HP Proteins for Homo sapiens (Human)

HP ELISA Kit

HP ELISA Kit for Homo sapiens (Human)