IL13RA1
IL13RA1,即白細(xì)胞介素13受體亞單位α1,別名NR4、CT19、CD213A1。它是由人類IL13RA1基因編碼的蛋白質(zhì),該基因位于X染色體上。IL13RA1是IL-13受體的主要結(jié)合亞基,與IL-4受體α形成受體復(fù)合體,這是IL-13和IL-4受體共有的亞基。IL13RA1與IL-13結(jié)合后,與IL-4受體α鏈形成異二聚體,激活JAK2/Tyk2依賴的信號轉(zhuǎn)導(dǎo)和轉(zhuǎn)錄激活因子STAT的磷酸化。IL13RA1在免疫調(diào)節(jié)、炎癥反應(yīng)、過敏反應(yīng)等多個生物學(xué)過程中發(fā)揮關(guān)鍵作用,對單核巨噬細(xì)胞、B淋巴細(xì)胞、NK細(xì)胞和血管內(nèi)皮細(xì)胞等具有多種生物學(xué)作用,是機(jī)體免疫反應(yīng)的重要調(diào)節(jié)介質(zhì)。
熱銷產(chǎn)品
Recombinant Human Interleukin-13 receptor subunit alpha-1 (IL13RA1) (CSB-CF011591HU)
驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
IL13RA1 Recombinant Monoclonal Antibody (CSB-RA011591MA1HU)
驗(yàn)證數(shù)據(jù)

IHC image of CSB-RA011591MA1HU diluted at 1:200 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
IL13RA1 Antibodies
IL13RA1 for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA003019 | IL13RA1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA009595 | Phospho-IL13RA1 (Y405) Antibody | Human,Mouse,Rat | WB, IF, ELISA |
CSB-PA058807 | IL13RA1 Antibody | Human | ELISA,IHC |
CSB-PA011591LA01HU | IL13RA1 Antibody | Human | ELISA, IHC, IF |
CSB-PA011591LB01HU | IL13RA1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA011591LC01HU | IL13RA1 Antibody, FITC conjugated | Human | |
CSB-PA011591LD01HU | IL13RA1 Antibody, Biotin conjugated | Human | ELISA |
CSB-RA011591MA1HU | IL13RA1 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
IL13RA1 Proteins
IL13RA1 Proteins for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011591HU1 CSB-EP011591HU1 CSB-BP011591HU1 CSB-MP011591HU1 CSB-EP011591HU1-B |
Recombinant Human Interleukin-13 receptor subunit alpha-1 (IL13RA1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011591HU | Recombinant Human Interleukin-13 receptor subunit alpha-1 (IL13RA1) | in vitro E.coli expression system |
CSB-AP004571HU | Recombinant Human Interleukin-13 receptor subunit alpha-1 (IL13RA1), partial (Active) | Mammalian cell |
CSB-MP011591HU | Recombinant Human Interleukin-13 receptor subunit alpha-1 (IL13RA1)-VLPs | Mammalian cell |
IL13RA1 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP011591MO1 CSB-EP011591MO1 CSB-BP011591MO1 CSB-MP011591MO1 CSB-EP011591MO1-B |
Recombinant Mouse Interleukin-13 receptor subunit alpha-1 (Il13ra1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF011591MO | Recombinant Mouse Interleukin-13 receptor subunit alpha-1 (Il13ra1) | in vitro E.coli expression system |