IL6RA
IL6RA，即白細(xì)胞介素-6受體亞單位α，別名CD126、IL-6R、IL-1Ra、IL6RA、gp80。它是一種I型跨膜糖蛋白，由多種細(xì)胞包括免疫細(xì)胞、上皮細(xì)胞和脂肪細(xì)胞分泌產(chǎn)生。IL6RA作為IL-6的激動(dòng)劑，通過(guò)與IL-6結(jié)合形成復(fù)合物，再與膜蛋白gp130結(jié)合，激活JAK/STAT、MAPK和Akt等信號(hào)通路，從而調(diào)節(jié)細(xì)胞生長(zhǎng)、分化，并在免疫反應(yīng)、急性期反應(yīng)和造血中發(fā)揮重要作用。IL6RA的失調(diào)與許多疾病的發(fā)病機(jī)制有關(guān)，如多發(fā)性骨髓瘤、自身免疫性疾病和前列腺癌等。
熱銷產(chǎn)品
Recombinant Human Interleukin-6 receptor subunit alpha (IL6R), partial (CSB-YP011665HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Interleukin 6 receptor(IL-6R)ELISA Kit (CSB-E16524h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E16524h
規(guī)格：96T/48T
靈敏度：0.039 ng/mL
檢測(cè)范圍：0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
IL6RA Antibodies
IL6RA for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006108 | IL6R Antibody | Human | WB, ELISA |
IL6RA Proteins
IL6RA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011665HU | Recombinant Human Interleukin-6 receptor subunit alpha (IL6R), partial | Yeast |
| CSB-EP011665HU CSB-BP011665HU CSB-MP011665HU CSB-EP011665HU-B |
Recombinant Human Interleukin-6 receptor subunit alpha (IL6R), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL6RA ELISA Kit
IL6RA ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E16524h | Human Interleukin 6 receptor(IL-6R)ELISA Kit | serum, plasma, tissue homogenates | 0.039 ng/mL |
