IL7
IL7，即白介素7，別名IL-7。它是一種由IL7基因編碼的25kDa大小的可溶性分泌蛋白，主要在骨髓基質(zhì)細胞中產(chǎn)生，也在胸腺、淋巴結(jié)、腸道、肺、肝和皮膚等多種組織中表達。IL7的作用機制主要是通過與其受體IL-7R結(jié)合來發(fā)揮作用，IL-7R是一種由IL-7Rα和γ鏈組成的異二聚體復(fù)合物。當IL-7與其受體結(jié)合后，會激活JAK1、JAK3和PI3K信號通路，進而激活A(yù)KT或STAT5，導(dǎo)致BCL-2家族成員表達變化，促進細胞存活和增殖。IL7在生物學(xué)上的意義非常廣泛，它對T細胞和B細胞的發(fā)育、幼稚T細胞的分化和存活以及記憶T細胞的生成和維持至關(guān)重要。IL7信號對多種免疫細胞的發(fā)育和維持起著不可或缺的作用，是適應(yīng)性免疫和保持免疫穩(wěn)態(tài)的關(guān)鍵。此外，IL7還在腫瘤治療中顯示出潛在的應(yīng)用價值，例如增強T細胞介導(dǎo)的抗腫瘤免疫反應(yīng)。
熱銷產(chǎn)品
IL7 Antibodies
IL7 for Human, Mouse
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011669KA01HU | IL7 Antibody | Human,Mouse | ELISA,WB,IHC |
IL7 Proteins
IL7 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011669MO CSB-EP011669MO CSB-BP011669MO CSB-MP011669MO CSB-EP011669MO-B |
Recombinant Mouse Interleukin-7 (Il7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003331MO | Recombinant Mouse Interleukin-7 protein (Il7) | E.Coli |
| CSB-AP004791MO | Recombinant Mouse Interleukin-7 (Il7) (Active) | Mammalian cell |
IL7 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011669HU CSB-EP011669HU CSB-BP011669HU CSB-EP011669HU-B |
Recombinant Human Interleukin-7 (IL7) | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP001751HU | Recombinant Human Interleukin-7 protein (IL7) | E.Coli |
| CSB-AP004441HU | Recombinant Human Interleukin-7 (IL7) (Active) | E.coli |
| CSB-AP004491HU | Recombinant Human Interleukin-7 (IL7) (Active) | Mammalian cell |
| CSB-AP005851HU | Recombinant Human Interleukin-7 (IL7) (Active) (GMP) | E.Coli |
| CSB-MP011669HU-WD | Recombinant Human Interleukin-7 (IL7) (Active) | Mammalian cell |
IL7 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011669BO CSB-BP011669BO CSB-MP011669BO CSB-EP011669BO-B |
Recombinant Bovine Interleukin-7 (IL7) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP011669BO | Recombinant Bovine Interleukin-7 (IL7) | E.coli |
IL7 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011669RA CSB-EP011669RA CSB-BP011669RA CSB-MP011669RA CSB-EP011669RA-B |
Recombinant Rat Interleukin-7 (Il7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL7 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP637907SH CSB-EP637907SH CSB-BP637907SH CSB-MP637907SH CSB-EP637907SH-B |
Recombinant Sheep Interleukin-7 (IL7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL7 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP865053PI CSB-EP865053PI CSB-BP865053PI CSB-MP865053PI CSB-EP865053PI-B |
Recombinant Pig Interleukin-7 (IL7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL7 Proteins for Homo sapiens(Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-CF011669HU | Recombinant Human Interleukin-7 (IL7) | in vitro E.coli expression system |
IL7 ELISA Kit
IL7 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E14032h | Human Interleukin-7,IL-7 ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 1.95 pg/mL |
| CSB-E14032h-IS | Human Interleukin-7,IL-7 ELISA kit | serum, plasma, tissue homogenates, cell culture supernates | 0.39 pg/mL |
IL7 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E10257m | Mouse Interleukin-7,IL-7 ELISA kit | serum, plasma, tissue homogenates | 0.039 ng/ml |
