JARID2
JARID2，別名JMJ、DIDDF。JARID2是一種DNA結(jié)合蛋白，起著轉(zhuǎn)錄抑制因子的作用。JARID2與Polycomb抑制復(fù)合物2（PRC2）相互作用，后者在胚胎發(fā)育過程中在調(diào)節(jié)基因表達(dá)方面起著重要作用。這種蛋白質(zhì)有助于將PRC2復(fù)合物募集到靶基因。JARID2在多種生理過程中發(fā)揮作用，包括細(xì)胞對白血病抑制因子的反應(yīng)、造血或淋巴器官發(fā)育以及基因表達(dá)的調(diào)控。JARID2的突變與多種疾病相關(guān)，如慢性骨髓性惡性腫瘤、非特異性綜合征智力障礙、法洛四聯(lián)癥、Weaver綜合征、Kabuki綜合征1、自閉癥譜系障礙等。
熱銷產(chǎn)品
JARID2 Antibody (CSB-PA852915HA01HU)
驗證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA852915HA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA852915HA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA852915HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
JARID2 Antibodies
JARID2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA852915HA01HU | JARID2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA852915HC01HU | JARID2 Antibody, FITC conjugated | Human | |
| CSB-PA852915HD01HU | JARID2 Antibody, Biotin conjugated | Human | ELISA |
JARID2 Proteins
JARID2 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP701873CH CSB-EP701873CH CSB-BP701873CH CSB-MP701873CH CSB-EP701873CH-B |
Recombinant Chicken Protein Jumonji (JARID2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
JARID2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP733821MO CSB-EP733821MO CSB-BP733821MO CSB-MP733821MO CSB-EP733821MO-B |
Recombinant Mouse Protein Jumonji (Jarid2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
JARID2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP852915HU CSB-EP852915HU CSB-BP852915HU CSB-MP852915HU CSB-EP852915HU-B |
Recombinant Human Protein Jumonji (JARID2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
