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Your Good Partner in Biology Research

KISS1R

KISS1R,即吻素1受體,別名GPR54、KISS1R1。它是一種G蛋白偶聯(lián)受體,由KISS1R基因編碼,在下丘腦和垂體等部位表達(dá)。KISS1R的作用機(jī)制涉及與吻素1(KISS1)結(jié)合,激活Gq/11蛋白,進(jìn)而促進(jìn)磷脂酰肌醇4,5-二磷酸(PIP2)轉(zhuǎn)化為肌醇三磷酸(IP3)和二酰甘油(DAG),調(diào)節(jié)細(xì)胞內(nèi)鈣離子濃度和蛋白激酶C(PKC)的活性。KISS1R在生物學(xué)上的意義主要體現(xiàn)在其對生殖系統(tǒng)、能量平衡和應(yīng)激反應(yīng)的調(diào)控作用。KISS1R的激活影響性激素的分泌和性行為,同時在調(diào)節(jié)食欲和身體組成方面發(fā)揮作用。此外,KISS1R的表達(dá)與神經(jīng)內(nèi)分泌疾病有關(guān),是相關(guān)疾病研究和治療的潛在靶點(diǎn)。

熱銷產(chǎn)品

KISS1R Antibody (CSB-PA248650)

驗(yàn)證數(shù)據(jù)

CSB-PA248650

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA248650(KISS1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA248650

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA248650(KISS1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

KISS1R Antibodies

KISS1R for Homo sapiens (Human)

KISS1R Proteins

KISS1R Proteins for Rattus norvegicus (Rat)

KISS1R Proteins for Mus musculus (Mouse)

KISS1R Proteins for Homo sapiens (Human)