KITLG

KITLG，即KIT配體，別名SCF、MGF、FPFH、DCUA等。它是一種由骨髓微環(huán)境中的基質細胞產生的酸性糖蛋白，由兩個相同亞基非共價結合而成。KITLG的作用機制主要是通過與其受體c-Kit結合，激活下游的信號傳導途徑，如JAK/STAT、PI3K/AKT、ERK1/2和STAT3等，從而促進細胞增殖、分化和遷移。KITLG在胚胎期的生殖細胞和神經細胞發(fā)育、造血過程中發(fā)揮作用，成體中主要在造血過程中發(fā)揮作用。KITLG的異常表達與多種疾病相關，包括家族性進行性高色素沉著癥、神經性耳聾、某些類型的癌癥如鼻咽癌、膀胱癌和三陰性乳腺癌。KITLG在腫瘤微環(huán)境中的表達與腫瘤細胞的增殖、侵襲和轉移密切相關，是癌癥治療中的潛在藥物靶點。

熱銷產品

Recombinant Human Kit ligand (KITLG), partial (Active) (CSB-MP002061HU1)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Activity
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of MO7e cells is 1.813-3.203 ng/mL.

The purity of KITLG was greater than 95% as determined by SEC-HPLC

KITLG Antibody

KITLG Protein

KITLG ELISA Kit

KITLG Antibodies

KITLG for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA012376ESR2HU	KITLG Antibody	Human	ELISA, WB
CSB-PA122514	KITLG Antibody	Human	ELISA,WB

KITLG Proteins

KITLG Proteins for Ovis aries (Sheep)

產品貨號	產品名稱	來源
CSB-YP012376SH1 CSB-EP012376SH1 CSB-BP012376SH1 CSB-MP012376SH1 CSB-EP012376SH1-B	Recombinant Sheep Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF012376SH	Recombinant Sheep Kit ligand (KITLG)	in vitro E.coli expression system

KITLG Proteins for Felis catus (Cat) (Felis silvestris catus)

產品貨號	產品名稱	來源
CSB-YP012376CA1 CSB-EP012376CA1 CSB-BP012376CA1 CSB-MP012376CA1 CSB-EP012376CA1-B	Recombinant Cat Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF012376CA	Recombinant Cat Kit ligand (KITLG)	in vitro E.coli expression system

KITLG Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-YP012376RA1 CSB-EP012376RA1 CSB-BP012376RA1 CSB-MP012376RA1 CSB-EP012376RA1-B	Recombinant Rat Kit ligand (Kitlg), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF012376RA	Recombinant Rat Kit ligand (Kitlg)	in vitro E.coli expression system

KITLG Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP012376MO1 CSB-EP012376MO1 CSB-BP012376MO1 CSB-EP012376MO1-B	Recombinant Mouse Kit ligand (Kitlg), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli
CSB-AP003151MO	Recombinant Mouse Kit ligand protein (Kitlg), partial (Active)	E.Coli
CSB-CF012376MO	Recombinant Mouse Kit ligand (Kitlg)	in vitro E.coli expression system
CSB-AP004071MO	Recombinant Mouse Kit ligand (Kitlg), partial (Active)	E.coli

KITLG Proteins for Mustela vison (American mink) (Neovison vison)

產品貨號	產品名稱	來源
CSB-YP012376MVE CSB-EP012376MVE CSB-BP012376MVE CSB-MP012376MVE CSB-EP012376MVE-B	Recombinant Mustela vison Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

產品貨號	產品名稱	來源
CSB-YP012376DXJ CSB-EP012376DXJ CSB-BP012376DXJ CSB-MP012376DXJ CSB-EP012376DXJ-B	Recombinant Coturnix coturnix japonica Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Capra hircus (Goat)

產品貨號	產品名稱	來源
CSB-YP012376GO CSB-EP012376GO CSB-BP012376GO CSB-MP012376GO CSB-EP012376GO-B	Recombinant Goat Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Equus caballus (Horse)

產品貨號	產品名稱	來源
CSB-YP012376HO CSB-EP012376HO CSB-BP012376HO CSB-MP012376HO CSB-EP012376HO-B	Recombinant Horse Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Gallus gallus (Chicken)

產品貨號	產品名稱	來源
CSB-YP012376CH CSB-EP012376CH CSB-BP012376CH CSB-MP012376CH CSB-EP012376CH-B	Recombinant Chicken Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP012376BO CSB-BP012376BO CSB-MP012376BO CSB-EP012376BO-B	Recombinant Bovine Kit ligand (KITLG), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Sus scrofa (Pig)

產品貨號	產品名稱	來源
CSB-YP012376PI CSB-EP012376PI CSB-BP012376PI CSB-MP012376PI CSB-EP012376PI-B	Recombinant Pig Kit ligand (KITLG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KITLG Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-EP012376HU	Recombinant Human Kit ligand (KITLG), partial	E.coli
CSB-AP002061HU	Recombinant Human Kit ligand protein (KITLG), partial (Active)	E.Coli
CSB-CF012376HU(A4)	Recombinant Human Kit ligand (KITLG)	in vitro E.coli expression system
CSB-AP003741HU	Recombinant Human Kit ligand (KITLG), partial (Active)	E.coli
CSB-AP003881HU	Recombinant Human Kit ligand (KITLG), partial (Active)	Mammalian cell
CSB-MP002061HU1h6	Recombinant Human Kit ligand (KITLG), partial	Mammalian cell
CSB-MP002061HU1	Recombinant Human Kit ligand (KITLG), partial (Active)	Mammalian cell
CSB-MP002061HU-WD	Recombinant Human Kit ligand (KITLG)，Partial (Active)	Mammalian cell