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LAMTOR2

Ragulator complex protein LAMTOR2 is a protein in humans that is encoded by LAMTOR2 gene. As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

LAMTOR2 Proteins

LAMTOR2 Proteins for Salmo salar (Atlantic salmon)

LAMTOR2 Proteins for Taeniopygia guttata (Zebra finch) (Poephila guttata)

LAMTOR2 Proteins for Bos taurus (Bovine)

LAMTOR2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

LAMTOR2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

LAMTOR2 Proteins for Mus musculus (Mouse)

LAMTOR2 Proteins for Homo sapiens (Human)