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LAMTOR4

Ragulator complex protein LAMTOR4 is a protein in humans that is encoded by LAMTOR4 gene. As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.

LAMTOR4 Proteins

LAMTOR4 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

LAMTOR4 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

LAMTOR4 Proteins for Homo sapiens (Human)

LAMTOR4 Proteins for Bos taurus (Bovine)

LAMTOR4 Proteins for Pongo abelii (Sumatran orangutan)

LAMTOR4 Proteins for Mus musculus (Mouse)