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MAGEA3

MAGEA3,也稱為人黑色素瘤抗原MAGE-A3,是一種在多種腫瘤中表達(dá)的腫瘤相關(guān)抗原。它通常不在正常人體細(xì)胞中表達(dá),除了睪丸和胎盤(pán)。MAGEA3蛋白在腫瘤免疫治療中扮演重要角色,因?yàn)樗梢猿蔀槊庖咧委煹陌悬c(diǎn)。在藥物研發(fā)方面,針對(duì)MAGEA3的免疫治療策略正在被探索,以激活免疫系統(tǒng)對(duì)抗腫瘤細(xì)胞。此外,MAGEA3蛋白的表達(dá)與多種癌癥的發(fā)生和發(fā)展密切相關(guān),如黑色素瘤、肺癌和胃癌等。

熱銷產(chǎn)品

Recombinant Human Melanoma-associated antigen 3 (MAGEA3) (CSB-EP013329HUb0)

驗(yàn)證數(shù)據(jù)

CSB-EP013329HUb0

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

MAGEA3 Antibody (CSB-PA013329LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA013329LA01HU

Western Blot
Positive WB detected in: A549 whole cell lysate, Jurkat whole cell lysate, 293T whole cell lysate
All lanes: MAGEA3 antibody at 4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 35 kDa
Observed band size: 35 kDa

CSB-PA013329LA01HU

IHC image of CSB-PA013329LA01HU diluted at 1:200 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA013329LA01HU

IHC image of CSB-PA013329LA01HU diluted at 1:200 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human melanoma-associated antigen 3 (MAGE-3) ELISA Kit (CSB-E15769h)

驗(yàn)證數(shù)據(jù)

CSB-E15769h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E15769h

規(guī)格:96T/48T

靈敏度:0.156 ng/mL

檢測(cè)范圍:0.625 ng/mL-40 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

MAGEA3 Antibodies

MAGEA3 for Homo sapiens (Human)

MAGEA3 Proteins

MAGEA3 Proteins for Homo sapiens (Human)

MAGEA3 ELISA Kit

MAGEA3 ELISA Kit for Homo sapiens (Human)