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MAP3K11

Mitogen-activated protein kinase kinase kinase 11 is a protein in humans that is encoded by MAP3K11 gene. Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

MAP3K11 Antibodies

MAP3K11 for Homo sapiens (Human)

MAP3K11 Proteins

MAP3K11 Proteins for Rattus norvegicus (Rat)

MAP3K11 Proteins for Mus musculus (Mouse)

MAP3K11 Proteins for Homo sapiens (Human)