MASP1
MASP1，即甘露聚糖結(jié)合凝集素相關(guān)絲氨酸蛋白酶1，別名MAP1、MBL associated serine protease 1等。它來源于人類的3號(hào)染色體，是一種血清中的糖蛋白，在先天免疫中通過凝集素途徑激活補(bǔ)體系統(tǒng)。MASP1的作用機(jī)制包括與甘露糖結(jié)合凝集素結(jié)合，形成復(fù)合物，通過裂解C4和C2產(chǎn)生C3轉(zhuǎn)化酶，激活補(bǔ)體系統(tǒng)，參與病原體的清除。此外，MASP1還能直接裂解C3產(chǎn)生C3b，參與補(bǔ)體旁路途徑的激活。MASP1在天然免疫中發(fā)揮重要作用，參與病原體識(shí)別和免疫應(yīng)答，同時(shí)在肝纖維化、腫瘤發(fā)生發(fā)展等病理過程中也有重要作用。
熱銷產(chǎn)品
Recombinant Human Mannan-binding lectin serine protease 1 (MASP1) (CSB-EP013508HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
MASP1 Antibody (CSB-PA013508LA01HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: MASP1 antibody at 6µg/ml
Lane 1: Hela whole cell lysate
Lane 2: U251 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 80, 82, 44, 69 kDa
Observed band size: 80 kDa
MASP1 Antibodies
MASP1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA000076 | Cleaved-MASP1 (R448) Antibody | Human | WB, ELISA |
| CSB-PA013508LA01HU | MASP1 Antibody | Human | ELISA, WB |
| CSB-PA013508LD01HU | MASP1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA013508LC01HU | MASP1 Antibody, FITC conjugated | Human | |
| CSB-PA013508LB01HU | MASP1 Antibody, HRP conjugated | Human | ELISA |
MASP1 Proteins
MASP1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013508MO CSB-EP013508MO CSB-BP013508MO CSB-MP013508MO CSB-EP013508MO-B |
Recombinant Mouse Mannan-binding lectin serine protease 1 (Masp1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MASP1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013508HU | Recombinant Human Mannan-binding lectin serine protease 1 (MASP1) | Yeast |
| CSB-EP013508HU | Recombinant Human Mannan-binding lectin serine protease 1 (MASP1) | E.coli |
| CSB-BP013508HU CSB-MP013508HU CSB-EP013508HU-B |
Recombinant Human Mannan-binding lectin serine protease 1 (MASP1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MASP1 ELISA Kit
MASP1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E17965h | Human mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (MASP1)ELISA kit | serum, plasma, tissue homogenates | 0.78 ng/mL |
