MCRS1
MCRS1，即微球蛋白1，別名P78、MCRS2、MSP58、INO80Q、ICP22BP。MCRS1是Ino80復(fù)合體、MLL1復(fù)合體及組蛋白乙酰轉(zhuǎn)移酶復(fù)合物的一部分，參與組蛋白H4乙?；?、DNA代謝過程的負調(diào)控以及蛋白質(zhì)定位到核仁的正向調(diào)節(jié)。
MCRS1的異常表達與多種疾病相關(guān)，尤其是腫瘤的發(fā)生和發(fā)展。MCRS1在肺癌、胰腺癌等實體瘤中高表達，并通過調(diào)控MHC-I分子的表達影響腫瘤細胞對免疫治療的敏感性，是新的治療靶點和預(yù)測指標。MCRS1還參與基因轉(zhuǎn)錄調(diào)節(jié)和細胞轉(zhuǎn)化等過程，對惡性腫瘤的發(fā)生及發(fā)展具有重要影響。
熱銷產(chǎn)品
MCRS1 Antibody (CSB-PA013611LA01HU)
驗證數(shù)據(jù)
Western blot
All lanes: MCRS1 antibody at 8μg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 52, 54, 51, 32 kDa
Observed band size: 52 kDa
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA013611LA01HU at dilution of 1:100
MCRS1 Antibodies
MCRS1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA013611GA01HU | MCRS1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA013611LA01HU | MCRS1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA013611LB01HU | MCRS1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA013611LC01HU | MCRS1 Antibody, FITC conjugated | Human | |
| CSB-PA013611LD01HU | MCRS1 Antibody, Biotin conjugated | Human | ELISA |
MCRS1 Proteins
MCRS1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013611HU CSB-EP013611HU CSB-BP013611HU CSB-MP013611HU CSB-EP013611HU-B |
Recombinant Human Microspherule protein 1 (MCRS1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
