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MEF2D

MEF2D,即肌細(xì)胞增強(qiáng)因子2D,別名Myocyte enhancer factor 2D。它是MADS盒家族的成員之一,參與多種細(xì)胞生命活動的調(diào)控。它通過與DNA上的MEF2結(jié)合位點(diǎn)相互作用,調(diào)控下游基因的轉(zhuǎn)錄,影響細(xì)胞增殖、分化、遷移和凋亡等過程。MEF2D在肌肉生成、神經(jīng)系統(tǒng)發(fā)育、肝纖維化以及腫瘤發(fā)展中扮演重要角色。特別是在腫瘤生物學(xué)中,MEF2D的異常表達(dá)與多種腫瘤的侵襲性、轉(zhuǎn)移能力和患者預(yù)后密切相關(guān),使其成為癌癥治療的潛在靶點(diǎn)。

熱銷產(chǎn)品

MEF2D Antibody (CSB-PA613522LA01HU)

驗證數(shù)據(jù)

CSB-PA613522LA01HU

Western Blot
Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, Mouse heart tissue
All lanes: MEF2D antibody at 2.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 56, 57, 51, 50 kDa
Observed band size: 56 kDa

CSB-PA613522LA01HU

IHC image of CSB-PA613522LA01HU diluted at 1:400 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA613522LA01HU

IHC image of CSB-PA613522LA01HU diluted at 1:400 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

MEF2D Antibodies

MEF2D for Homo sapiens (Human)

MEF2D Proteins

MEF2D Proteins for Rattus norvegicus (Rat)

MEF2D Proteins for Homo sapiens (Human)

MEF2D Proteins for Mus musculus (Mouse)